Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Crous-Bou M, Minguillón C, Gramunt N, Molinuevo JL.
Alzheimer's disease prevention: from risk factors to early intervention
Alzheimer's Research & TherapyAbstractDue to the progressive aging of the population, Alzheimer's disease (AD) is becoming a healthcare burden of epidemic proportions for which there is currently no cure. Disappointing results from...
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Demirtaş M, Falcon C, Tucholka A, Gispert JD, Molinuevo JL, Deco G.
A whole-brain computational modeling approach to explain the alterations in resting-state functional connectivity during progression of Alzheimer's disease
Neuroimage: ClinicalAbstractAlzheimer's disease (AD) is the most common dementia with dramatic consequences. The research in structural and functional neuroimaging showed altered brain connectivity in AD. In this study, we...
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Rojas S, Herance JR, Gispert JD, Arias B, Miquel I, Lopez R, Sanchez P, Rincon E, Murat J.
Characterization of the Biodistribution and Systemic Absorption of TT-173, a New Hemostatic Agent of Recombinant Human Tissue Factor, Using Radiolabeling with 18F
European Journal of Drug Metabolism and PharmacokineticsAbstractBackground and objectives: TT-173 is the first topical hemostatic agent based on tissue factor. To prevent thromboembolic events and intravascular coagulation it is necessary to rule out the systemic...
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Vert C, Sánchez-Benavides G, Martínez D, Gotsens X, Gramunt N, Cirach M, Molinuevo JL, Sunyer J, Nieuwenhuijsen MJ, Gascon M
Effect of long-term exposure to air pollution on anxiety and depression in adults: A cross-sectional study
International Journal of Hygiene and Environmental HealthAbstractBackground: The association between exposure to air pollutants and mental disorders among adults has been suggested, although results are not consistent. Objective: To analyze the association between...
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Frisoni GB, Boccardi M, Barkhof F, Blennow K, Cappa S, Chiotis K, Démonet JF, Garibotto V, Giannakopoulos P, Gietl A, Hansson O, Herholz K, Jack CR Jr, Nobili F, Nordberg A, Snyder HM, Ten Kate M, Varrone A, Albanese E, Becker S, Bossuyt P, Carrillo MC, Cerami C, Dubois B, Gallo V, Giacobini E, Gold G, Hurst S, Lönneborg A, Lovblad KO, Mattsson N, Molinuevo JL.
Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers
The Lancet NeurologyAbstractThe diagnosis of Alzheimer's disease can be improved by the use of biological measures. Biomarkers of functional impairment, neuronal loss, and protein deposition that can be assessed by neuroimaging...
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Tort-Merino A, Valech N, Peñaloza C, Grönholm-Nyman P, León M, Olives J, Estanga A, Ecay-Torres M, Fortea J, Martínez-Lage P, Molinuevo JL, Laine M, Rodríguez-Fornells A, Rami L
Early Detection of Learning Difficulties when Confronted with Novel Information in Preclinical Alzheimer's Disease Stage 1
Journal of Alzheimer's DiseaseAbstractWe employed a highly demanding experimental associative learning test (the AFE-T) to explore memory functioning in Preclinical Alzheimer's Disease stage 1 (PreAD-1) and stage 2 (PreAD-2). The task... -
Engelborghs S, Niemantsverdriet E, Molinuevo JL, Wallin A, Winblad B, Zetterberg H, Duits F, Teunissen CE
Consensus guidelines for lumbar puncture in patients with neurological diseases
Alzheimer's Dementia: Diagnosis, Assessment & Disease MonitoringAbstractIntroduction: Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic workup of several neurological brain diseases. Reluctance to perform the procedure is among others...
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Simonsen AH, Herukka SK, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczyńska A, Molinuevo JL, Mroczko B, Nordberg A, Oliveira CR, Otto M, Rinne JO, Rot U, Saka E, Soininen H, Struyfs H, Suardi S, Visser PJ, Winblad B, Zetterberg H, Waldemar G.
Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia
Alzheimer's & DementiaAbstractThis article presents recommendations, based on the Grading of Recommendations, Assessment, Development, and Evaluation method, for the clinical application of cerebrospinal fluid (CSF) amyloid-β1-42...
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Molinuevo JL, Rabin LA, Amariglio R, Buckley R, Dubois B, Ellis KA, Ewers M, Hampel H, Kloppel S, Rami L, Reisberg B, Saykin AJ, Sikkes S, Smart CM, Snitz BE, Sperling R, van der Flier WM, Wagner M, Jessen F, Subjective Cognitive Decline Initiative Working G
Implementation of subjective cognitive decline criteria in research studies
Alzheimer's & DementiaAbstractIntroduction: Subjective cognitive decline (SCD) manifesting before clinical impairment could serve as a target population for early intervention trials in Alzheimer's disease (AD). A working group... -
Brugulat-Serrat A, Rojas S, Bargalló N, Conesa G, Minguillón C, Fauria K, Gramunt, Molinuevo JL, Gispert JD
Incidental findings on brain MRI of cognitively normal first-degree descendants of patients with Alzheimer's disease: a cross-sectional analysis from the ALFA (Alzheimer and Families) project
BMJ OpenAbstractObjectives: To describe the prevalence of brain MRI incidental findings (IF) in a cohort of cognitively normal first-degree descendants of patients with Alzheimer's disease (AD). Design: Cross...
