Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Diaz-Ponce AM, Campill S, Barbera M, Birck C, Soldevila-Domenech N, Forcano Gamazo L, Ayala-Garcia A, Mangialasche F, Bruinsma J, Zwan M, Hartmann T, De La Torre-Fornell R, Solomon A.
"This also matters to me": what does adherence to dementia risk reduction interventions mean to members of the public?
Aging clinical and experimental researchAbstractGrowing evidence highlights the potential of multidomain lifestyle-based interventions to reduce the risk of cognitive decline among older adults at higher risk of cognitive impairment. Within these...
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Kac PR, González-Escalante A, Milà-Alomà M, Ashton NJ, Shekari M, Ortiz-Romero P, Turton M, Harrison P, Zetterberg H, Gispert JD, Karikari TK, Suárez-Calvet M, Blennow K.
Plasma p-tau212 identifies cognitively unimpaired individuals with emerging amyloid-β pathology
Journal of neurologyAbstractPlasma phosphorylated-tau (p-tau) biomarkers show high performance as first-in-line tests in the evaluation of patients with cognitive symptoms and have also found utility in clinical trials for anti...
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Bollack A, Shekari M, Collij LE, Luckett E, García DV, Markiewicz P, Wolz R, Yaqub M, Wink AM, Gismondi R, Stephens A, Visser PJ, Mett A, Drzezga A, Buckley C, Gispert JD, Farrar G, Barkhof F.
Implementing robust amyloid PET quantification in multi-center studies: AMYPAD approach to address data acquisition, processing, interpretation and data sharing challenges
Alzheimer's & DementiaAbstractIntroduction: Amyloid-positron emission tomography (PET) is pivotal to Alzheimer's management, with the Centiloid standardizing measurements across tracers. AMYPAD trials (Diagnostic and Patient...
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Porta-Mas C, Grau-Rivera O, Gispert JD, Blasco GS, Sánchez-Benavides G.
Validation status of cognitive digital assessments by the FDA BEST framework and context of use in preclinical AD studies: A systematic review
Alzheimer's & DementiaAbstractDigital cognitive assessments have rapidly expanded in Alzheimer's disease (AD) research, offering a sensitive, scalable, and cost-effective alternative to traditional neuropsychological tests. This...
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Valletta M, Briel N, Yuksekel I, Barboure M, Coward A, De Houwer JFH, Fawad A, González-Mayoral A, Iaccarino G, Martínez-Dubarbie F, Moukaled S, Andreasson U, Gobom J, Brinkmalm A, Tijms B, Zetterberg H, Blennow K, Suárez-Calvet M, Schöll M, Paterson RW, Montoliu-Gaya L, Sogorb-Esteve A.
Fluid biomarkers for neurodegenerative diseases: a comprehensive update
Alzheimer's Research & Therapy -
Pérez-García G, Gallart-Gallego L, Comps-Vicente O, Molto-García L, Grau-Rivera O, Pradas-Méndez S, Soteras-Prat A, Montes-Pérez A.
Protocol to avoid post-dural puncture headache after large-volume cerebral spinal fluid extraction in a prospective observational memory clinic study
Scientific ReportsAbstractLumbar puncture (LP) to extract cerebral spinal fluid (CSF) to quantify analytes relevant to brain health can lead to post-dural puncture headache (PDPH). Incidences vary across studies. This...
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Ibáñez A, Duran-Aniotz C, Migeot J, Báez S, Fittipaldi S, Coronel-Oliveros C, Eyre HA, Udeh-Momoh C, Zetterberg H, Alladi S, Sandi C, Robertson IH, Franzen S, Farombi T, Montalvo Ortiz JL, Seshadri S, Court F, Valdes-Sosa P, Xu J, Yu C, Grinberg L, Lawlor B, Sachdev PS, Yaffe K, Hachinski V, Friston K, Tagliazucchi E, Santamaría-García H.
Computational whole-body-exposome models for global precision brain health
Nature CommunicationsAbstractThe worldwide rise of neurological and psychiatric conditions poses major challenges. However, current global research remains fragmented, dominated by limited cohorts and poorly integrated datasets...
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Xia X, Eriksdotter M, Zetterberg H, Kern S, Skillbäck T, Blasi MT, Winblad B, Mak JKL, Ornago AM, Pinardi E, Romero Ortuño R, Jönsson L
Frailty and prognosis of biomarker-confirmed Alzheimer's disease: a Swedish, register-based, retrospective cohort study
The Lancet Healthy LongevityAbstractBackground: This study aimed to examine the value of frailty status (defined by the frailty index) in informing the prognosis of people living with Alzheimer's disease.
Methods: In this retrospective...
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International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative
Alzheimer's Research & TherapyAbstractBackground: Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical practice and no consensus exists as to a uniform operationalization of socio-cognitive measures for NCDs...
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Borràs E, Anastasi F, Pastor O, Suárez-Calvet M, Sabidó E
Enhanced proteome profiling of human cerebrospinal fluid using a commercial plasma enrichment strategy
Journal of proteomicsAbstractCerebrospinal fluid (CSF) is a valuable liquid biopsy for identifying protein biomarkers in neurological diseases, yet its proteome profiling faces challenges due to the large dynamic range of protein...
