Publications
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Rodríguez-Fernández B, Sánchez-Benavides G, Genius P, Minguillon C, Fauria K, De Vivo I, Navarro A, Molinuevo JL, Gispert JD, Sala-Vila A, Vilor-Tejedor N, Crous-Bou M.
Association between telomere length and cognitive function among cognitively unimpaired individuals at risk of Alzheimer's disease
AbstractIntroduction: Leukocyte telomere length (LTL) is an objective biomarker of biological aging, and it is proposed to play a crucial role in Alzheimer's disease (AD) risk. We aimed at evaluating the...
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Falcon C, Montesinos P, Václavů L, Kassinopoulos M, Minguillon C, Fauria K, Cascales-Lahoz D, Contador J, Fernández-Lebrero A, Navalpotro I, Puig-Pijoan A, Grau-Rivera O, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Zetterberg H, Blennow K, Suárez-Calvet M, Van Osch MJP, Sanchez-Gonzalez J, Gispert JD.
Time-encoded ASL reveals lower cerebral blood flow in the early AD continuum
AbstractIntroduction: Cerebral blood flow (CBF) is reduced in cognitively impaired (CI) Alzheimer's disease (AD) patients. We checked the sensitivity of time-encoded arterial spin labeling (te-ASL) in...
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Pujol J, Blanco-Hinojo L, Persavento C, Martínez-Vilavella G, Falcón C, Gascón M, Rivas I, Vilanova M, Deus J, Gispert JD, Gómez-Roig MD, Llurba E, Dadvand P, Sunyer J.
Functional structure of local connections and differentiation of cerebral cortex areas in the neonate
AbstractNeuroimaging research on functional connectivity can provide valuable information on the developmental differentiation of the infant cerebral cortex into its functional areas. We examined healthy...
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Lázaro I, Grau-Rivera O, Suárez-Calvet M, Fauria K, Minguillón C, Shekari M, Falcón C, García-Prat M, Huguet J, Molinuevo JL, Gispert JD, Sala-Vila A.
Omega-3 blood biomarkers relate to brain glucose uptake in individuals at risk of Alzheimer's disease dementia
AbstractIntroduction: Brain glucose hypometabolism is a preclinical feature of Alzheimer's disease (AD). Dietary omega-3 fatty acids promote brain glucose metabolism, but clinical research is incipient...
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Dounavi ME, Mak E, Operto G, Muniz-Terrera G, Bridgeman K, Koychev I, Malhotra P, Naci L, Lawlor B, Su L, Falcon C, Ritchie K, Ritchie CW, Gispert JD, O'Brien JT.
Texture-based morphometry in relation to apolipoprotein ε4 genotype, ageing and sex in a midlife population
AbstractBrain atrophy and cortical thinning are typically observed in people with Alzheimer's disease (AD) and, to a lesser extent, in those with mild cognitive impairment. In asymptomatic middle-aged...
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Shekari M, Vállez García D, Collij LE, Altomare D, Heeman F, Pemberton H, Roé Vellvé N, Bullich S, Buckley C, Stephens A, Farrar G, Frisoni G, Klunk WE, Barkhof F, Gispert JD.
ADNI and the AMYPAD consortium. Stress testing the Centiloid: Precision and variability of PET quantification of amyloid pathology. Alzheimers Dement
AbstractIntroduction: Assessing the potential sources of bias and variability of the Centiloid (CL) scale is fundamental for its appropriate clinical application.
Methods: We included 533 participants from...
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Evans TE, Vilor-Tejedor N, Operto G, Falcon C, Hofman A, Ibáñez A, Seshadari S, Tan LC, Weiner M, Alladi S, Anazodo U, Gispert Lopez JD.
Structural brain differences in the Alzheimer's disease continuum: Insights into the heterogeneity from a large multi-site neuroimaging consortium
AbstractIntroduction: Neurodegenerative diseases require collaborative, multi-site research to comprehensively grasp their complex and diverse pathological progression, yet there is caution in aggregating...
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Stankeviciute L, Chhatwal JP, Levin R, Pinilla V, Schultz AP, Redline S, Johnson KA, Sperling RA, Kozhemiako N, Purcell S, Djonlagic I.
Amyloid beta-independent sleep markers associated with early regional tau burden and cortical thinning
AbstractIntroduction: Sleep is crucial for memory consolidation and the clearance of toxic proteins associated with Alzheimer's disease (AD). We examined the association between sleep characteristics and...
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Lorenzini L, Collij LE, Tesi N, Vilor-Tejedor N, Ingala S, Blennow K, Foley C, Frisoni GB, Haller S, Holstege H, van der van der Lee S, Martinez-Lage P, Marioni RE, McCartney DL, O' Brien J, Oliveira TG, Payoux P, Reinders M, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Waldman AD, Wolz R, Chatelat G, Ewers M, Wink AM, Mutsaerts HJMM, Gispert JD, Visser PJ, Tijms BM, Altmann A, Barkhof F.
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals
AbstractIntroduction: Unraveling how Alzheimer's disease (AD) genetic risk is related to neuropathological heterogeneity, and whether this occurs through specific biological pathways, is a key step toward...
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Ghaziri J, Fei P, Tucholka A, Obaid S, Boucher O, Rouleau I, Nguyen DK.
Resting-State Functional Connectivity Profile of Insular Subregions
AbstractThe insula is often considered the fifth lobe of the brain and is increasingly recognized as one of the most connected regions in the brain, with widespread connections to cortical and subcortical...
