Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Oosthoek M, Vijverberg EGB, Blujdea ER, Veld SGJGI, Avilés MP, Zsadanyi SE, Hok-A-Hin YS, Visser A, van der Flier WM, Barkhof F, Del Campo M, Schut MC, Bejanin A, Alcolea D, Teunissen CE, Vermunt L.
CHIT1 and DDAH1 levels relate to amyloid-related imaging abnormalities risk profile in Alzheimer's disease patients
Alzheimer's Research & TherapyAbstractBackground: Amyloid-related imaging abnormalities (ARIA) are a common and potentially dangerous side effect in anti-amyloid therapies, creating a need for tools to assess ARIA risk. Several patient...
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Palmqvist S, Whitson HE, Allen LA, Suarez-Calvet M, Galasko D, Karikari TK, Okrahvi HR, Paczynski M, Schindler SE, Teunissen CE, Zetterberg H, Carrillo MC, Edelmayer RM, Mahinrad S, McAteer MB, Kahale LA, Pahlke S, Tampi MP.
Alzheimer's Association Clinical Practice Guideline on the use of blood-based biomarkers in the diagnostic workup of suspected Alzheimer's disease within specialized care settings
Alzheimer's & DementiaAbstractObjective and scope: A panel of clinicians, subject-matter experts, and guideline methodologists convened by the Alzheimer's Association conducted a systematic review and formulated evidence-based...
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Buongiorno M, Tur C, Giraldo DM, Cullell N, Krupinski J, Lanzillo R, Sánchez-Benavides G
Sleep and Risk of Multiple Sclerosis: Bridging the Gap Between Inflammation and Neurodegeneration via Glymphatic Failure
Brain SciencesAbstractEpidemiological studies identified insufficient and poor-quality sleep as independent risk factors for multiple sclerosis (MS). The glymphatic system, active during slow-wave sleep, clears brain waste...
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Suárez-Calvet M, Abdelnour C, Alcolea D, Mendióroz-Iriarte M, Balasa M, Morenas-Rodríguez E, Puig-Pijoan A, Sánchez-Juan P, Villarejo A, Sánchez-Valle R; por el Grupo de trabajo en biomarcadores en sangre del Grupo de Estudio de Conducta y Demencias de la Sociedad Española de Neurología.
Blood-based Biomarkers for Alzheimer's Disease: Positioning Document and Usage Recommendations from the Behavioral Neurology and Dementia Study Group of the Spanish Society of Neurology
NeurologíaAbstractIntroduction: The development of blood biomarkers for detecting Alzheimer's disease (AD) represents one of the most significant recent advances, and some are already available for clinical practice...
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Ossenkoppele R, Coomans EM, Apostolova LG, Baker SL, Barthel H, Beach TG, Benzinger TLS, Betthauser T, Bischof GN, Bottlaender M, Bourgeat P, den Braber A, Brendel M, Brickman AM, Cash DM, Carrillo MC, Coath W, Christian BT, Dickerson BC, Dore V, Drzezga A, Feizpour A, van der Flier WM, Franzmeier N, Frisoni GB, Garibotto V, van de Giessen E, Domingo-Gispert J, Gnoerich J, Gu Y, Guan Y, Hanseeuw BJ, Harrison TM, Jack CR, Jaeger E, Jagust WJ, Jansen WJ, La Joie R, Johnson KA, Johnson SC, Kennedy IA, Kim JP, van Laere K, Lagarde J, Lao P, Luchsinger JA, Kern S, Kreisl WC, Malotaux V, Malpetti M, Manly JJ, Mao X, Mattsson-Carlgren N; Mayo Clinic Study on Aging; Messerschmidt K, Minguillon C, Mormino EM, O'Brien JT, Palmqvist S, Peretti DE, Petersen RC, Pijnenburg YAL, Pontecorvo MJ, Poirier J; PREVENT-AD Research Group; Rabinovici GD, Rahmouni N, Risacher SL, Rosa-Neto P, Rosen H, Rowe CC, Rowe JB, Rullmann M, Salman Y, Sarazin M, Saykin AJ, Schneider JA, Schöll M, Schott JM, Seo SW, Serrano GE, Shcherbinin S, Shekari M, Skoog I, Smith R, Sperling RA, Spruyt L, Stomrud E, Strandberg O, Therriault J, Xie F, Vandenberghe R, Villemagne VL, Villeneuve S, Visser PJ, Vossler H, Young CB, Groot C, Hansson O
Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
Nature NeuroscienceAbstractTau positron emission tomography (PET) imaging allows in vivo detection of tau proteinopathy in Alzheimer's disease, which is associated with neurodegeneration and cognitive decline. Understanding how...
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Imam F, Saloner R, Vogel JW, Krish V, Abdel-Azim G, Ali M, An L, Anastasi F, Bennett D, Pichet Binette A, Boxer AL, Bringmann M, Burns JM, Cruchaga C, Dage JL, Farinas A, Ferrucci L, Finney CA, Frasier M, Hansson O, Hohman TJ, Johnson ECB, Kivimaki M, Korologou-Linden R, Ruiz Laza A, Levey AI, Liepelt-Scarfone I, Lu L, Mattsson-Carlgren N, Middleton LT, Nho K, Oh HS, Petersen RC, Reiman EM, Robinson O, Rothstein JD, Saykin AJ, Shvetcov A, Slawson C, Smets B, Suárez-Calvet M, Tijms BM, Timmers M, Vieira F, Vilor-Tejedor N, Visser PJ, Walker KA, Winchester LM, Wyss-Coray T, Yang C, Bose N, Lovestone S
he Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging
Nature MedicineAbstractMore than 57 million people globally suffer from neurodegenerative diseases, a figure expected to double every 20 years. Despite this growing burden, there are currently no cures, and treatment...
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Forcano L, Soldevila-Domenech N, Boronat A, Sánchez-Benavides G, Puig-Pijoan A, Lorenzo T, Aldea-Perona A, Suárez-Calvet M, Cuenca-Royo A, Gispert JD, Gomis- Gonzalez M, Minguillón C, Diaz-Pellicer P, Fauria K, Piera I, Langohr K, Dierssen M, Pizarro N, Mur-Gimeno E, Grau-Rivera O, Molinuevo JL, de la Torre R.
A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial
The journal of prevention of Alzheimer's DiseaseAbstractBackground: The potential of dietary compounds to enhance the effects of multimodal lifestyle interventions (MLIs) on cognition in individuals at high risk of cognitive impairment remains unclear.
Obje...
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Lorenzo T, Ngandu T, Lehtisalo J, Antikainen R, Gispert JD, Kemppainen N, Laatikainen T, Lindström J, Rinne J, Soininen H, Strandberg T, Torre R, Tuomilehto J, Solomon A, Kivipelto M.
Associations of Prediabetes, Diabetes and Glucose-Related Markers With Cognition and Neuroimaging in a 2-Year Multidomain Lifestyle Randomised Controlled Trial.
Diabetes/Metabolism research and reviewsAbstractAims: Few longitudinal studies have explored Oral Glucose Tolerance Test markers (OGTT) and both cognitive and brain changes. We investigated OGTT and other glycaemia and insulin resistance markers...
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Contador I, Akinci M, Palpatzis E, Aguilar-Domínguez P, Deulofeu C, Fuentes-Julian S, Fauria K, Minguillón C, Grau-Rivera O, Sánchez-Benavides G, Arenaza-Urquijo EM
Psychological resilience trajectories after the COVID-19 pandemic: the role of lifestyle and psychosocial factors in a cohort at increased alzheimer's disease risk
Social psychiatry and psychiatric epidemiologyAbstractPurpose: This longitudinal cohort study evaluates whether lifestyle and psychosocial factors are associated with psychological resilience at two time points of COVID-19 pandemic. Moreover, we...
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Stankeviciute L, Tort-Colet N, Fernández-Arcos A, Sánchez-Benavides G, Minguillón C, Fauria K, Holst SC, Garcés P, Mueggler T, Zetterberg H, Blennow K, Iranzo Á, Suárez-Calvet M, Gispert JD, Molinuevo JL, Grau-Rivera O
Associations between objective sleep metrics and brain structure in cognitively unimpaired adults: interactions with sex and Alzheimer's biomarkers
Alzheimer's & DementiaAbstractIntroduction: Sleep disturbances are prevalent in Alzheimer's disease (AD), probably emerging during its preclinical stage. Poor subjective sleep quality is linked to reduced brain volume and cortical...
