Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Operto G, Cacciaglia R, Grau O, Falcón C, Brugulat-Serrat A, Ródenas P, Ramos R, Morán S, Esteller M, Bargalló N, Molinuevo JL, Gispert JD
White matter microstructure is altered in cognitively normal middle-aged APOE-ε4 homozygotes
Alzheimer's Research & TherapyAbstractBackground: The ε4 allele of the apolipoprotein E gene (APOE-ε4) is the strongest genetic factor for late-onset Alzheimer's disease. During middle age, cognitively healthy APOE-ε4 carriers already...
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Gascon M, Sánchez-Benavides G, Dadvand P, Martínez D, Gramunt N, Gotsens X, Cirach M, Vert C, Molinuevo JL, Nieuwenhuijsen M
Long-term exposure to residential green and blue spaces and anxiety and depression in adults: A cross-sectional study
Environmental ResearchAbstractBackground: Although exposure to natural outdoor environments has been consistently associated with improved perceived general health, available evidence on a protective association between this...
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Rojas S, Brugulat-Serrat A, Bargalló N, Minguillón C, Tucholka A, Falcon C, Carvalho A, Morán S, Esteller M, Gramunt N, Fauria K, Camí J, Molinuevo JL, Gispert JD
Higher prevalence of cerebral white matter hyperintensities in homozygous APOE-ɛ4 allele carriers aged 45-75: Results from the ALFA study
Journal of Cerebral Blood Flow & MetabolismAbstractCerebral white matter hyperintensities are believed the consequence of small vessel disease and are associated with risk and progression of Alzheimer's disease. The ɛ4 allele of the APOE gene is the...
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Tucholka A, Grau-Rivera O, Falcon C, Rami L, Sánchez-Valle R, Lladó A, Gispert JD, Molinuevo JL, for the Alzheimer’s Disease Neuroimaging Initiative
Structural connectivity alterations along the AD continuum: reproducibility across two independent samples and correlation with CSF Aβ and tau
Journal of Alzheimer's DiseaseAbstractBackground: Gray matter changes associated with the progression of Alzheimer's disease (AD) have been thoroughly studied. However, alterations in white matter tracts have received less attention...
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Vert C, Sánchez-Benavides G, Martínez D, Gotsens X, Gramunt N, Cirach M, Molinuevo JL, Sunyer J, Nieuwenhuijsen MJ, Gascon M
Effect of long-term exposure to air pollution on anxiety and depression in adults: A cross-sectional study
International Journal of Hygiene and Environmental HealthAbstractBackground: The association between exposure to air pollutants and mental disorders among adults has been suggested, although results are not consistent. Objective: To analyze the association between...
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Modeling practice effects in healthy middle-aged participants of the Alzheimer and Families parent cohort
Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringAbstractIntroduction: Repetitive administration of neuropsychological tests can lead to performance improvement merely due to previous exposure. The magnitude of such practice effects (PEs) may be used as a...
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Sánchez-Benavides G, Peña-Casanova J, Casals-Coll M, Gramunt N, Manero RM, Puig-Pijoan A, Aguilar M, Robles A, Antúnez C, Frank-García A, Fernández-Martínez M, Blesa R, NEURONORMA Study Team
One-Year Reference Norms of Cognitive Change in Spanish Old Adults: Data from the NEURONORMA Sample.
Archives of Clinical NeuropsychologyAbstractObjective: Serial cognitive assessments are useful for many purposes, such as monitoring cognitive decline or evaluating the result of an intervention. In order to determine if an observed change is...
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Molinuevo JL, Gramunt N, Gispert JD, Fauria K, Esteller M, Minguillon C, Sánchez-Benavides G, Huesa G, Morán S, Camí J.
The ALFA project: a research platform to identify early pathophysiological features of Alzheimer’s disease
Alzheimer's & Dementia: Translational Research & Clinical InterventionsAbstractIntroduction: The preclinical phase of Alzheimer's disease (AD) is optimal for identifying early pathophysiological events and developing prevention programs, which are shared aims of the ALFA project...
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Gramunt N, Sánchez-Benavides G, Buschke H, Dieguez-Vide F, Pena-Casanova J, Masramon X, Fauria K, Gispert JD, Molinuevo JL
The Memory Binding Test: Development of Two Alternate Forms into Spanish and Catalan
Journal of Alzheimer's DiseaseAbstractBackground: The Memory Binding Test (MBT) is emerging as a promising tool for the detection of subtle memory impairment suggestive of Alzheimer's disease (AD). For such a test to be widely accessed...
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Gramunt N, Sánchez-Benavides G, Buschke H, Lipton RB, Masramon X, Gispert JD, Pena-Casanova J, Fauria K, Molinuevo JL
Psychometric Properties of the Memory Binding Test: Test-Retest Reliability and Convergent Validity
Journal of Alzheimer's DiseaseAbstractBackground: Episodic memory testing is fundamental for the diagnosis of Alzheimer's disease (AD). Although the Free and Cued Selective Reminding Test (FCSRT) is widely used for this purpose, it may...
