Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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van Maurik IS, Altomare D, Collij LE, Caprioglio C, Moro C, Garibotto V, Demonet JF, Scheltens P, Farrer G, Gismondi R, Stephens AW, Gispert JD, Molinuevo JL, Grau-Rivera O, Edison P, Walker Z, Jessen F, Dzrezga A, Zeyen P, Payoux P, Saint-Aubert L, Delrieu J, Nordberg A, Barkhof F, Frisoni GB, Berkhof J
Costs and Cost-Utility of Amyloid-PET in the Diagnostic Process of Memory Clinic Patients
European Journal of NeurologyAbstractBackground: Amyloid positron emission tomography (PET) is instrumental in achieving an accurate diagnosis and may help to limit health-seeking behavior. Currently, amyloid-PET is not routinely used in...
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González-Escalante A, Milà-Alomà M, Brum WS, Ashton NJ, Ortiz-Romero P, Shekari M, Campo MD, Anastasi F, Quijano-Rubio C, Kollmorgen G, Minguillón C, Sánchez-Benavides G, Grau-Rivera O, Gispert JD, Zetterberg H, Vilor-Tejedor N, Blennow K, Suárez-Calvet M.
A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer's disease
EBioMedicineAbstractBackground: Plasma biomarkers of Alzheimer's disease (AD) change during preclinical stages, indicating potential for detecting amyloid-β (Aβ) pathology in cognitively unimpaired (CU) individuals...
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López-Martos D, Brugulat-Serrat A, Suárez-Calvet M, Milà-Alomà M, Minguillon C, Domingo Gispert J, Zetterberg H, Blennow K, Grau-Rivera O, Sánchez-Benavides G
Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers
NeuropsychologyAbstractObjective: Neuropsychological norms serve to identify cognitive impairment and monitor neurodegenerative disease progression. However, longitudinal data are limited, and conventional approaches do not...
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Laurell AAS, Mak E, Dounavi ME, Underwood BR, Dauvilliers Y, Dudas RB, Marguet O, Ritchie CW, Koychev I, Lawlor BA, Naci L, Malhotra P, Grau-Rivera O, Gispert JD, O'Brien JT
Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults. Alzheimers Dement
Alzheimer's & DementiaAbstractIntroduction: Sleep dysfunction in those at higher risk of dementia may be associated with early structural changes to the hypothalamus.
Methods: We used multivariate regression to analyze self...
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Cumplido-Mayoral I, Sánchez-Benavides G, Vilor-Tejedor N, López-Martos D, Brugulat-Serrat A, Milà-Alomà M, Falcon C, Cacciaglia R, Minguillón C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Suárez-Calvet M, Vilaplana V, Gispert JD
Neuroimaging-derived biological brain age and its associations with glial reactivity and synaptic dysfunction cerebrospinal fluid biomarkers.
Molecular PsychiatryAbstractMagnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other...
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Palpatzis E, Akinci M, Garcia-Prat M, Blennow K, Zetterberg H, Quijano-Rubio C, Kollmorgen G, Wild N, Gispert JD, Suárez-Calvet M, Grau-Rivera O, Fauria K, Brugulat-Serrat A, Sanchez-Benavides G, Arenaza-Urquijo EM; ALFA stydy
Grief and Economic Stressors by Sex, Gender, and Education: Associations With Alzheimer Disease-Related Outcomes
NeurologyAbstractBackground and objectives: The prevalence and impact of stressful life events (SLEs) on age-related and Alzheimer disease (AD)-related pathways may depend on social determinants including gender and...
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Frisoni GB, Ribaldi F, Allali G, Bieth T, Brioschi Guevara A, Cappa S, Cipolotti L, Frederiksen KS, Georges J, Jessen F, Koch G, Masters H, Mendes AJ, Frölich L, Garibotto V, Grau-Rivera O, Pozzi FE, Religa D, Rostamzadeh A, Shallcross L, Shenkin SD, van der Flier WM, Vernooij MW, Visser LNC, Cummings JL, Scheltens P, Dubois B, Moro E, Bassetti CLA, Kivipelto M.
Brain health services for the secondary prevention of cognitive impairment and dementia: Opportunities, challenges, and the business case for existing and future facilities
The journal of prevention of Alzheimer's DiseaseAbstractA European Task Force has recently developed and published the concept and protocols for the setup of the innovative health offer of Brain Health Services for the secondary prevention of dementia and...
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Soldevila-Domenech N, Ayala-Garcia A, Barbera M, Lehtisalo J, Forcano L, Diaz-Ponce A, Zwan M, van der Flier WM, Ngandu T, Kivipelto M, Solomon A, de la Torre R.
Adherence and intensity in multimodal lifestyle-based interventions for cognitive decline prevention: state-of-the-art and future directions
Alzheimer's Research & TherapyAbstractPreventing dementia and Alzheimer's disease (AD) is a global priority. Multimodal interventions targeting several risk factors and disease mechanisms simultaneously are currently being tested...
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Sánchez-Benavides G, Iranzo A, Grau-Rivera O, Giraldo DM, Buongiorno M
Olfactory Dysfunction as a Clinical Marker of Early Glymphatic Failure in Neurodegenerative Diseases
DiagnosticsAbstractAn abnormal accumulation of misfolded proteins is a common feature shared by most neurodegenerative disorders. Olfactory dysfunction (OD) is common in the elderly population and is present in 90% of...
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Kuhn E, Klinger HM, Amariglio RE, Wagner M, Jessen F, Düzel E, Heneka MT, Chételat G, Rentz DM, Sperling RA, Ebenau JL, Butterbrod E, Van Der Flier WM, Sikkes SAM, Teunnissen CE, Van Harten AC, Van De Giessen EM, Rami L, Tort A, Sánchez Benavides G, Gifford KA, Van Hulle C, Buckley RF.
SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies
Alzheimer's & DementiaAbstractIntroduction: Specific features of subjective cognitive decline (SCD-plus) have been proposed to indicate an increased risk of preclinical Alzheimer's disease (AD). However, few studies have examined...
