Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Mattsson-Carlgren N, Palmqvist S, Horie K, Barthélemy N, Salvadó G, Binette AP, Tideman P, Morris JC, Benzinger TL, Perrin RJ, Janelidze S, Collij LE, Ossenkoppele R, Schindler SE, Stomrud E, Bateman RJ, Hansson O.
Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study
The Lancet NeurologyAbstractBackground: Alzheimer's disease pathology can be accurately identified with blood biomarkers (core 1 biomarkers), including plasma p-tau217 tests. Biomarkers that change longitudinally after diagnosis...
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Hortsch S, Domenico AD, Borlinghaus N, Caley D, Kaminioti-Dumont L, Jeppesen SB, González-Escalante A, Ritchie C, Frederiksen KS, Suárez-Calvet M.
Performance of a fully automated plasma tau phosphorylated at threonine 217 immunoassay to reflect amyloid-beta burden in an unselected cohort representative of clinical practice
The journal of prevention of Alzheimer's DiseaseAbstractBackground: With the emergence of disease-modifying anti-amyloid-beta (Aβ) therapies for Alzheimer's disease (AD), early and accurate quantitative measures of Aβ burden are critical. Blood-based...
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Salemme S, Mukadam N, Bodryzlova Y, Blossom SCM, Brayne C, Richard E, Seshadri S, Ma'u E, Akinyemi RO, Urso D, Wolters FJ, Grasset L, Dufouil C, Ferri CP, Langa KM, Kalaria R, McKenzie BL, Röhr S, Ibáñez A, Lautenschlage NT, Cullum S, Bobrow K, Anstey KJ, Wallace L, Walsh S; PLADRR Research Group.
Operationalising dementia prevention as a measurable NCD priority
The Lancet. Public HealthAbstractNot available
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Reiman EM, Alexander RC, Langbaum JB, Aisen PS, Ashton N, Atri A, Barbarino P, Byrd GS, Feldman HH, Fowler NR, Ghisays V, Grill JD, Hassenstab J, Heaton GR, Herring WL, Jack CR Jr, Johnson SC, Karlawish J, Keach NL, Kivipelto M, Krumholz HM, Largent EA, MaGee-Rodgers T, McDade E, Mielke MM, Molina-Henry D, Petersen RC, Rabinovici GD, Ritchie C, Schindler SE, Sperling RA, Suárez-Calvet M, Vradenburg G, Weiner MW, Welsh-Bohmer KA, Zetterberg H, Zuendel MT, Mattke S, Cummings JL
A path to preventing cognitive impairment due to Alzheimer's disease: initiatives beginning in the USA
The Lancet NeurologyAbstractAntibody therapies can remove amyloid plaques from the brain and slow cognitive decline in people with Alzheimer's disease who are mildly impaired. These drugs are now being evaluated in participants...
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Suemoto CK, Custodio N, Aguilar D, Avila-Funes JA, Baez S, Bagnati PM, Barnes LL, Brucki SMD, Calandri IL, Caramelli P, Cornejo-Olivas M, Derio CD, Ferreira ST, García AM, Grinberg LT, Ibanez AM, Isasi R, Josephy-Hernández SE, Porras ML, Llibre-Guerra JJ, Llibre-Rodriguez JJ, Lourenco MV, Meza BMM, Migeot J, Miranda JJ, Miranda-Castillo C, Mummery CJ, Parodi JF, Castro NP, Contreras RMS, Santamaría-García H, Slachevsky A, Souza-Talarico JN, Surace EI, Takada LT, Tsoy E, Pilalumbo MU, Zimmer ER, Fontana IC, Mahinrad S, Snyder HM, Carrillo MC.
The landscape of dementia research, diagnosis, treatment, and care in Latin America
Alzheimer's & DementiaAbstractLatin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed...
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Daly T, López-Barrenechea I, Vergara P, Arshad F, Paplikar A, Ray Chaudhuri A, Crivelli L, Ibáñez A, Alladi S, Slachevsky A.
Scientific knowledge about dementia: From the Global South to the world
Alzheimer's & DementiaAbstractMost people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines...
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Ibanez A, Roth N, Colverson A, Bailey C, Miller B, Durón-Reyes DE, Johnson N, Castaner O, Sacco PL, Cotter E, Melloni L.
Music as a scientific metaphor for mind and brain
Neuroscience and behavioural reviewsAbstractMetaphors have long played multiple roles in conceptualizing the mind and brain, guiding the development and refinement of theoretical models and empirical questions. Early analogies (comparing the...
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Kassinopoulos M, Montesinos P, Falcon C, Huguet J, Minguillon C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Zetterberg H, Blennow K, Suárez-Calvet M, Sanchez-Gonzalez J, Gispert JD; ALFA study
Intracellular fluid accumulation underlies brain volume increases in early Alzheimer's disease
Brain CommunicationsAbstractIn the preclinical stages of Alzheimer's disease, increased brain volume has been associated with amyloid-beta pathology, particularly in regions that undergo volume reductions as the disease...
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Canevelli M, Pomati S, Salati E, Maestri G, Sarti G, Calia C, Pecorari C, Marchetti S, Cova I, Nielsen TR, Jørgensen K, Kjaergaard D, Sciancalepore F, Nuti F, Toccaceli Blasi M, Pantoni L, Vanacore N, Bruno G.
Validation of the brief assessment of impaired cognition (BASIC) and brief assessment of impaired cognition questionnaire (BASIC-Q) in Italy
Neurological SciencesAbstractBackground: Brief and accurate tools are needed to enhance the prompt identification of cognitive disorders. This study aimed to translate and adapt two recently developed, highly accurate instruments...
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Blujdea ER, van Bokhoven P, Martino-Adami PV, Marshe VS, Vromen EM, Hok-A-Hin YS, Boiten WA, Irwin DJ, Chen-Plotkin AS, Lemstra AW, Pijnenburg Y, van der Flier WM, Peters O, Hellmann-Regen J, Priller J, Schneider A, Wiltfang J, Jessen F, Düzel E, Buerger K, Perneczky R, Teipel S, Laske C, Brosseron F; DELCODE Consortium; Del Campo M, Wijdeven R, Visser PJ, Tijms BM, De Jager PL, Ramirez A, Teunissen CE, Vermunt L.
Microglia protein profiles in CSF across Alzheimer's disease clinical stages
Nature AgingAbstractMicroglia are implicated in the progression of Alzheimer's disease (AD) pathology from its earliest stages, suggesting that cerebrospinal fluid (CSF) microglia profiling across clinical AD stages can...
