Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Genius P, Fernández-Bonet A, Rodríguez-Fernández B, Gallay C, Gonzalez-Escalante A, Sánchez-Benavides G, López-Martos D, Esteller M, Navarro A, Gispert JD, Brugulat-Serrat A, Vilor-Tejedor N
Sex-specific early cognitive changes are linked to global and pathway-specific genetic risk for Alzheimer's disease in at-risk individuals
Biology of sex differencesAbstractAlzheimer's disease (AD) is a progressive neurodegenerative condition in which genetic predisposition plays a key role, yet the sex-specific mechanisms linking genetic risk to early cognitive changes...
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Piromalli D, Cañadas-Romero MA, Ivirico-Prats M, Suárez-Calvet M, Beriain Bañares A, Sánchez-Valle M, Ortíz-Castelví L.
Areaalzheimer: development of a digital platform for caregivers based on the results of a needs analysis and mixed-methods pilot evaluation process
Frontiers in Digital HealthAbstractIntroduction: This study describes the user-centred design and evaluation of AreAreaAlzheimer, a web-based digital platform developed to support family caregivers of individuals with dementia...
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Forcano L, Soldevila-Domenech N, Boronat A, Sánchez-Benavides G, Puig-Pijoan A, Lorenzo T, Aldea-Perona A, Suárez-Calvet M, Cuenca-Royo A, Gispert JD, Gomis- Gonzalez M, Minguillón C, Diaz-Pellicer P, Fauria K, Piera I, Langohr K, Dierssen M, Pizarro N, Mur-Gimeno E, Grau-Rivera O, Molinuevo JL, de la Torre R.
A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial
The journal of prevention of Alzheimer's DiseaseAbstractBackground: The potential of dietary compounds to enhance the effects of multimodal lifestyle interventions (MLIs) on cognition in individuals at high risk of cognitive impairment remains unclear.
Obje...
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Contador I, Akinci M, Palpatzis E, Aguilar-Domínguez P, Deulofeu C, Fuentes-Julian S, Fauria K, Minguillón C, Grau-Rivera O, Sánchez-Benavides G, Arenaza-Urquijo EM
Psychological resilience trajectories after the COVID-19 pandemic: the role of lifestyle and psychosocial factors in a cohort at increased alzheimer's disease risk
Social psychiatry and psychiatric epidemiologyAbstractPurpose: This longitudinal cohort study evaluates whether lifestyle and psychosocial factors are associated with psychological resilience at two time points of COVID-19 pandemic. Moreover, we...
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Stankeviciute L, Tort-Colet N, Fernández-Arcos A, Sánchez-Benavides G, Minguillón C, Fauria K, Holst SC, Garcés P, Mueggler T, Zetterberg H, Blennow K, Iranzo Á, Suárez-Calvet M, Gispert JD, Molinuevo JL, Grau-Rivera O
Associations between objective sleep metrics and brain structure in cognitively unimpaired adults: interactions with sex and Alzheimer's biomarkers
Alzheimer's & DementiaAbstractIntroduction: Sleep disturbances are prevalent in Alzheimer's disease (AD), probably emerging during its preclinical stage. Poor subjective sleep quality is linked to reduced brain volume and cortical...
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van Maurik IS, Altomare D, Collij LE, Caprioglio C, Moro C, Garibotto V, Demonet JF, Scheltens P, Farrer G, Gismondi R, Stephens AW, Gispert JD, Molinuevo JL, Grau-Rivera O, Edison P, Walker Z, Jessen F, Dzrezga A, Zeyen P, Payoux P, Saint-Aubert L, Delrieu J, Nordberg A, Barkhof F, Frisoni GB, Berkhof J
Costs and Cost-Utility of Amyloid-PET in the Diagnostic Process of Memory Clinic Patients
European Journal of NeurologyAbstractBackground: Amyloid positron emission tomography (PET) is instrumental in achieving an accurate diagnosis and may help to limit health-seeking behavior. Currently, amyloid-PET is not routinely used in...
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González-Escalante A, Milà-Alomà M, Brum WS, Ashton NJ, Ortiz-Romero P, Shekari M, Campo MD, Anastasi F, Quijano-Rubio C, Kollmorgen G, Minguillón C, Sánchez-Benavides G, Grau-Rivera O, Gispert JD, Zetterberg H, Vilor-Tejedor N, Blennow K, Suárez-Calvet M.
A plasma biomarker panel for detecting early amyloid-β accumulation and its changes in middle-aged cognitively unimpaired individuals at risk for Alzheimer's disease
EBioMedicineAbstractBackground: Plasma biomarkers of Alzheimer's disease (AD) change during preclinical stages, indicating potential for detecting amyloid-β (Aβ) pathology in cognitively unimpaired (CU) individuals...
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López-Martos D, Brugulat-Serrat A, Suárez-Calvet M, Milà-Alomà M, Minguillon C, Domingo Gispert J, Zetterberg H, Blennow K, Grau-Rivera O, Sánchez-Benavides G
Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers
NeuropsychologyAbstractObjective: Neuropsychological norms serve to identify cognitive impairment and monitor neurodegenerative disease progression. However, longitudinal data are limited, and conventional approaches do not...
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Laurell AAS, Mak E, Dounavi ME, Underwood BR, Dauvilliers Y, Dudas RB, Marguet O, Ritchie CW, Koychev I, Lawlor BA, Naci L, Malhotra P, Grau-Rivera O, Gispert JD, O'Brien JT
Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults. Alzheimers Dement
Alzheimer's & DementiaAbstractIntroduction: Sleep dysfunction in those at higher risk of dementia may be associated with early structural changes to the hypothalamus.
Methods: We used multivariate regression to analyze self...
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Cumplido-Mayoral I, Sánchez-Benavides G, Vilor-Tejedor N, López-Martos D, Brugulat-Serrat A, Milà-Alomà M, Falcon C, Cacciaglia R, Minguillón C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Suárez-Calvet M, Vilaplana V, Gispert JD
Neuroimaging-derived biological brain age and its associations with glial reactivity and synaptic dysfunction cerebrospinal fluid biomarkers.
Molecular PsychiatryAbstractMagnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other...
