Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Dubbelman MA, Verrijp M, Facal D, Sánchez-Benavides G, Brown LJE, van der Flier WM, Jokinen H, Lee A, Leroi I, Lojo-Seoane C, Milošević V, Molinuevo JL , Pereiro Rozas AX, Ritchie C, Salloway S, Stringer G, Zygouris S, Dubois B, Epelbaum S, Scheltens P, Sikkes SAM.
The Influence of Diversity on the Measurement of Functional Impairment: An International Validation of the Amsterdam IADL Questionnaire in Eight Countries
Alzheimers Dement (Amst)AbstractIntroduction: To understand the potential influence of diversity on the measurement of functional impairment in dementia, we aimed to investigate possible bias caused by age, gender, education, and...
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Crous-Bou M, Gascon M, Gispert JD, Cirach M, Sánchez-Benavides G, Falcon C, Arenaza-Urquijo EM, Gotsens X, Fauria K, Sunyer J, Nieuwenhuijsen MJ, Molinuevo JL
Impact of Urban Environmental Exposures on Cognitive Performance and Brain Structure of Healthy Individuals at Risk for Alzheimer's Dementia
Environ IntAbstractBackground: Air quality might contribute to incidence of dementia-related disorders, including Alzheimer's dementia (AD). The aim of our study is to evaluate the effect of urban environmental...
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Eider M Arenaza-Urquijo, Prashanthi Vemuri
Improving the resistance and resilience framework for aging and dementia studies
Alzheimer's Research & TherapyAbstractBackground: The "resistance vs resilience" to Alzheimer's disease (AD) framework (coping vs avoiding) has gained interest in the field in the last year. In this viewpoint, our effort is (i) to provide...
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Heeman F, Yaqub M, Lopes Alves I, Heurling K, Bullich S, Gispert JD , Boellaard R, Lammertsma AA; AMYPAD Consortium.
Simulating the Effect of Cerebral Blood Flow Changes on Regional Quantification of [ 18 F]flutemetamol and [ 18 F]florbetaben Studies
J Cereb Blood Flow MetabAbstractGlobal and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of these...
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Cacciaglia R , Molinuevo JL , Falcón C , Arenaza-Urquijo EM , Sánchez-Benavides G , Brugulat-Serrat A, Blennow K, Gispert JD
APOE-ε4 Shapes the Cerebral Organization in Cognitively Intact Individuals as Reflected by Structural Gray Matter Networks
Cereb CortexAbstractGray matter networks (GMn) provide essential information on the intrinsic organization of the brain and appear to be disrupted in Alzheimer's disease (AD). Apolipoprotein E (APOE)-ε4 represents the...
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Jecmenica Lukic M, Kurz C, Respondek G, Grau-Rivera O , Compta Y, Gelpi E, Troakes C; Barcelona Brain Bank collaborative group, the MDS-endorsed PSP study group, van Swieten JC, Giese A, Roeber S, Arzberger T, Höglinger G.
Copathology in Progressive Supranuclear Palsy: Does It Matter?
Mov DisordAbstractBackground: The influence of concomitant brain pathologies on the progression rate in PSP is unclear. Objectives: To analyze the frequency and severity of copathologies and their impact on the...
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Stavros Skouras, Jordi Torner, Patrik Andersson, Yury Koush, Carles Falcon, Carolina Minguillon, Karine Fauria, Francesc Alpiste, Kaj Blenow, Henrik Zetterberg, Juan D Gispert, José L Molinuevo, ALFA Study
Earliest amyloid and tau deposition modulate the influence of limbic networks during closed-loop hippocampal down-regulation
BrainAbstractResearch into hippocampal self-regulation abilities may help determine the clinical significance of hippocampal hyperactivity throughout the pathophysiological continuum of Alzheimer's disease. In...
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Skouras S, Torner J, Andersson P, Koush Y, Falcon C, Minguillon C, Fauria K, Alpiste F, Blenow K, Zetterberg H, Gispert JD, Molinuevo JL
Earliest Amyloid and Tau Deposition Modulate the Influence of Limbic Networks During Closed-Loop Hippocampal Downregulation
BrainAbstractResearch into hippocampal self-regulation abilities may help determine the clinical significance of hippocampal hyperactivity throughout the pathophysiological continuum of Alzheimer's disease. In... -
Shared Latent Structures Between Imaging Features and Biomarkers in Early Stages of Alzheimer's Disease: A Predictive Study
IEEE J Biomed Health InformAbstractMagnetic resonance imaging (MRI) provides high resolution brain morphological information and is used as a biomarker in neurodegenerative diseases. Population studies of brain morphology often seek to... -
Vilor-Tejedor N , Ikram MA, Roshchupkin GV, Cáceres A, Alemany S, Vernooij MW, Niessen WJ, van Duijn CM, Sunyer J, Adams HH, González JR
Independent Multiple Factor Association Analysis for Multiblock Data in Imaging Genetics
NeuroinformaticsAbstractMultivariate methods have the potential to better capture complex relationships that may exist between different biological levels. Multiple Factor Analysis (MFA) is one of the most popular methods to...
