Read the latest news about research and scientific resultats on Alzheimer's disease at the Barcelonaβeta Brain Research Center (BBRC).
The results, published in The New England Journal of Medicine, confirm that lecanemab slows cognitive decline by 27% in patients in the early stages of Alzheimer's disease.
A study led by the Hospital del Mar Medical Research Institute, the Barcelonaβeta Brain Research Centre and the University of Gothenburg has compared the validity of nine biomarkers for the day-to-day diagnosis of Alzheimer's disease in hospital centres.
The research, within the European project EPAD, is headed by the Barcelonaβeta Brain Research Center (BBRC), a research center of the Pasqual Maragall Foundation, together with the University of Bristol.
In the research, led by the BBRC, 250 people without cognitive alterations from the ALFA Study, promoted by the ”la Caixa” Foundation, have participated.
More than 900 people without cognitive alterations from the Alfa Study, which has the support of the "la Caixa" Foundation, have participated in the research.
The study, which used data from almost 400 participants of the ALFA+ Study, determines that the biomarkers p-tau231 and p-tau217 measured in the blood are suitable for indicating brain changes related to the amyloid protein in people without cognitive symptoms.
Research helps to better understand the relationship between biomarkers of Alzheimer’s disease and the pathophysiological mechanisms that are altered in their early stages.
The thesis develved into urrent knowledge of the disease during its preclinical stage and provides new evidence for its early detection.
Researchers at the Pasqual Maragall Foundation's research center, the Barcelonaβeta Brain Research Center (BBRC), with the support of the “la Caixa” Foundation, have detected that the glial fibrillar acid protein (GFAP) is a very accurate biomarker for diagnosing in blood the early stages of Alzheimer’s disease.