Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Ibanez A, Roth N, Colverson A, Bailey C, Miller B, Durón-Reyes DE, Johnson N, Castaner O, Sacco PL, Cotter E, Melloni L.
Music as a scientific metaphor for mind and brain
Neuroscience and behavioural reviewsAbstractMetaphors have long played multiple roles in conceptualizing the mind and brain, guiding the development and refinement of theoretical models and empirical questions. Early analogies (comparing the...
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Scher, M.S., Eyre, H.A., Adalat, S., Hartikainen, K., Berk, M., Ibanez, A. & Markvarde, A.
Childhood health through matrescence empowers women to sustain life-course brain health
npj Women's HealthAbstractThe spectrum from normal brain functions to neurological and mental health disorders represents the life-course neural exposome. Proactive interventions strengthen rescue and reparative choices...
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Kassinopoulos M, Montesinos P, Falcon C, Huguet J, Minguillon C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Zetterberg H, Blennow K, Suárez-Calvet M, Sanchez-Gonzalez J, Gispert JD; ALFA study
Intracellular fluid accumulation underlies brain volume increases in early Alzheimer's disease
Brain CommunicationsAbstractIn the preclinical stages of Alzheimer's disease, increased brain volume has been associated with amyloid-beta pathology, particularly in regions that undergo volume reductions as the disease...
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Canevelli M, Pomati S, Salati E, Maestri G, Sarti G, Calia C, Pecorari C, Marchetti S, Cova I, Nielsen TR, Jørgensen K, Kjaergaard D, Sciancalepore F, Nuti F, Toccaceli Blasi M, Pantoni L, Vanacore N, Bruno G.
Validation of the brief assessment of impaired cognition (BASIC) and brief assessment of impaired cognition questionnaire (BASIC-Q) in Italy
Neurological SciencesAbstractBackground: Brief and accurate tools are needed to enhance the prompt identification of cognitive disorders. This study aimed to translate and adapt two recently developed, highly accurate instruments...
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Blujdea ER, van Bokhoven P, Martino-Adami PV, Marshe VS, Vromen EM, Hok-A-Hin YS, Boiten WA, Irwin DJ, Chen-Plotkin AS, Lemstra AW, Pijnenburg Y, van der Flier WM, Peters O, Hellmann-Regen J, Priller J, Schneider A, Wiltfang J, Jessen F, Düzel E, Buerger K, Perneczky R, Teipel S, Laske C, Brosseron F; DELCODE Consortium; Del Campo M, Wijdeven R, Visser PJ, Tijms BM, De Jager PL, Ramirez A, Teunissen CE, Vermunt L.
Microglia protein profiles in CSF across Alzheimer's disease clinical stages
Nature AgingAbstractMicroglia are implicated in the progression of Alzheimer's disease (AD) pathology from its earliest stages, suggesting that cerebrospinal fluid (CSF) microglia profiling across clinical AD stages can...
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Orellana P, Caviedes A, Gonzalez L, Ochoa-Rosales C, Carmona D, González-Silva C, Hernández H, Britton GB, Villarreal AE, Campos V, Hendrie H, Acosta-Uribe J, Pina-Escudero SD, Yokoyama JS, Vilor-Tejedor N, Parra M, Santamaria-García H, Ibañez A, de la Cruz R, Duran-Aniotz C
Association of apolipoprotein E variants on Alzheimer's disease in Latin America: A systematic review and meta-analysis
Alzheimer's & DementiaAbstractThe apolipoprotein E (APOE) ε4 allele represents the strongest genetic risk factor for Alzheimer's disease (AD), but its role in genetically diverse Latin American and Caribbean (LAC) populations is...
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Brugulat-Serrat A, Tsoy E, Sánchez-Benavides G, Milà-Alomà M, Gaynor LS, Grau-Rivera O, Gispert JD, Kramer JH, Possin KL
European Prevention of Alzheimer's Disease (EPAD) Consortium. Detecting early memory changes in preclinical Alzheimer's disease using TabCAT favorites test: Data from the European Prevention of Alzheimer's Disease (EPAD) cohort
Alzheimer's & DementiaAbstractIntroduction: Sensitive memory paradigms may allow the detection of subtle memory changes associated with early Alzheimer's pathology in individuals without established clinical symptomatology.
Methods...
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Falgàs N, Tort-Colet N, Martín-Sobrino I, Mayà G, Peña-González M, Rudilosso S, Gaig C, Bosch B, Arqueros A, Pérez-Millan A, Tort-Merino A, Fernández-Villullas G, Piñol-Ripoll G, Balasa M, Lladó A, Ruiz MM, Muñoz-Moreno E, Grau-Rivera O, Iranzo A, Grinberg LT, Sánchez-Valle R.
Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease
Alzheimer's & DementiaAbstractIntroduction: Sleep disruption, particularly loss of slow-wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus...
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Genius P, Fernández-Bonet A, Rodríguez-Fernández B, Gallay C, Gonzalez-Escalante A, Sánchez-Benavides G, López-Martos D, Esteller M, Navarro A, Gispert JD, Brugulat-Serrat A, Vilor-Tejedor N
Sex-specific early cognitive changes are linked to global and pathway-specific genetic risk for Alzheimer's disease in at-risk individuals
Biology of sex differencesAbstractAlzheimer's disease (AD) is a progressive neurodegenerative condition in which genetic predisposition plays a key role, yet the sex-specific mechanisms linking genetic risk to early cognitive changes...
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Bolsewig K, Bellomo G, Hok-A-Hin YS, Al Idrissi I, Vermunt L, Lleó A, Alcolea D, Sieben A, Engelborghs S, Simonsen AH, Hasselbalch SG, Bech S, Morrema THJ, Hoozemans JJM, Bol JGJM, van Alphen J, Gaetani L, Chiasserini D, Paolini Paoletti F, Parnetti L, Kang S, Lee YG, Jeon S, Lee A, Jeon S, Ye BS, Del Campo Milán M, van der Flier WM, van de Berg WDJ, Lemstra AW, Willemse EAJ, Teunissen CE
A quantitative DOPA decarboxylase biomarker for diagnosis in Lewy body disorders
Nature MedicineAbstractAccurate diagnosis of dementia with Lewy bodies (DLB) remains challenging, with misdiagnosis potentially leading to harmful treatment decisions. DOPA decarboxylase (DDC) shows promise as a...
