Artículos sobre Alzheimer
Artículos científicos publicados por los investigadores del Barcelonaβeta Brain Research Center (BBRC), relacionados con la enfermedad de Alzheimer, neuroimagen, memoria y enfermedades neurodegenerativas, entre otros campos.
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Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, Ritchie C, Scheltens P, Schwarz AJ, Sudre CH, Tijms BM, Verde F, Ticozzi N, Silani V, Visser PJ, Waldman A, Wolz R, Chételat G, Ewers M, Wink AM, Mutsaerts H, Gispert JD, Wardlaw JM, Barkhof F.
Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia
NeurologyAbstractBackground and objectives: Vascular risk factors (VRFs) and cerebral small vessel disease (cSVD) are common in patients with Alzheimer disease (AD). It remains unclear whether this coexistence...
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Schöll M, Verberk IMW, Del Campo M, Delaby C, Therriault J, Chong JR, Palmqvist S, Alcolea D.
Challenges in the practical implementation of blood biomarkers for Alzheimer's disease
The Lancet Healthy LongevityAbstractBlood biomarkers have emerged as accessible, cost-effective, and highly promising tools for advancing the diagnostics of Alzheimer's disease. However, transitioning from cerebrospinal fluid biomarkers...
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Tristão-Pereira C, Fuster V, Lopez-Jimenez A, Fernández-Pena A, Semerano A, Fernandez-Nueda I, Garcia-Lunar I, Ayuso C, Sanchez-Gonzalez J, Ibanez B, Gispert JD, Cortes-Canteli M.
Subclinical atherosclerosis and brain health in midlife: Rationale and design of the PESA-Brain study
American Heart JournalAbstractRationale: Cognitive decline and dementia have been reportedly linked to atherosclerosis, the main cause of cardiovascular disease. Cohort studies identifying early brain alterations associated with...
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Rodríguez-Fernández B, Sánchez-Benavides G, Genius P, Minguillon C, Fauria K, De Vivo I, Navarro A, Molinuevo JL, Gispert JD, Sala-Vila A, Vilor-Tejedor N, Crous-Bou M.
Association between telomere length and cognitive function among cognitively unimpaired individuals at risk of Alzheimer's disease
Neurobiol AgingAbstractIntroduction: Leukocyte telomere length (LTL) is an objective biomarker of biological aging, and it is proposed to play a crucial role in Alzheimer's disease (AD) risk. We aimed at evaluating the...
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Falcon C, Montesinos P, Václavů L, Kassinopoulos M, Minguillon C, Fauria K, Cascales-Lahoz D, Contador J, Fernández-Lebrero A, Navalpotro I, Puig-Pijoan A, Grau-Rivera O, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Zetterberg H, Blennow K, Suárez-Calvet M, Van Osch MJP, Sanchez-Gonzalez J, Gispert JD.
Time-encoded ASL reveals lower cerebral blood flow in the early AD continuum
Alzheimers DementAbstractIntroduction: Cerebral blood flow (CBF) is reduced in cognitively impaired (CI) Alzheimer's disease (AD) patients. We checked the sensitivity of time-encoded arterial spin labeling (te-ASL) in...
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Pujol J, Blanco-Hinojo L, Persavento C, Martínez-Vilavella G, Falcón C, Gascón M, Rivas I, Vilanova M, Deus J, Gispert JD, Gómez-Roig MD, Llurba E, Dadvand P, Sunyer J.
Functional structure of local connections and differentiation of cerebral cortex areas in the neonate
NeuroImageAbstractNeuroimaging research on functional connectivity can provide valuable information on the developmental differentiation of the infant cerebral cortex into its functional areas. We examined healthy...
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Lázaro I, Grau-Rivera O, Suárez-Calvet M, Fauria K, Minguillón C, Shekari M, Falcón C, García-Prat M, Huguet J, Molinuevo JL, Gispert JD, Sala-Vila A.
Omega-3 blood biomarkers relate to brain glucose uptake in individuals at risk of Alzheimer's disease dementia
Alzheimers DementAbstractIntroduction: Brain glucose hypometabolism is a preclinical feature of Alzheimer's disease (AD). Dietary omega-3 fatty acids promote brain glucose metabolism, but clinical research is incipient...
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Dounavi ME, Mak E, Operto G, Muniz-Terrera G, Bridgeman K, Koychev I, Malhotra P, Naci L, Lawlor B, Su L, Falcon C, Ritchie K, Ritchie CW, Gispert JD, O'Brien JT.
Texture-based morphometry in relation to apolipoprotein ε4 genotype, ageing and sex in a midlife population
Human Brain MappingAbstractBrain atrophy and cortical thinning are typically observed in people with Alzheimer's disease (AD) and, to a lesser extent, in those with mild cognitive impairment. In asymptomatic middle-aged...
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Shekari M, Vállez García D, Collij LE, Altomare D, Heeman F, Pemberton H, Roé Vellvé N, Bullich S, Buckley C, Stephens A, Farrar G, Frisoni G, Klunk WE, Barkhof F, Gispert JD.
ADNI and the AMYPAD consortium. Stress testing the Centiloid: Precision and variability of PET quantification of amyloid pathology. Alzheimers Dement
Alzheimers DementAbstractIntroduction: Assessing the potential sources of bias and variability of the Centiloid (CL) scale is fundamental for its appropriate clinical application.
Methods: We included 533 participants from...
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Evans TE, Vilor-Tejedor N, Operto G, Falcon C, Hofman A, Ibáñez A, Seshadari S, Tan LC, Weiner M, Alladi S, Anazodo U, Gispert Lopez JD.
Structural brain differences in the Alzheimer's disease continuum: Insights into the heterogeneity from a large multi-site neuroimaging consortium
Biological Psychiatry: Cognitive Neuroscience and NeuroimagingAbstractIntroduction: Neurodegenerative diseases require collaborative, multi-site research to comprehensively grasp their complex and diverse pathological progression, yet there is caution in aggregating...
