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publicaciones

Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.

  • Toccaceli Blasi M, Salzillo M, Buscarnera S, Nuti F, Stanziale C, Pecorari C, Ottone DA, Salati E, D'Antonio F, Canevelli M, Bruno G.

    A diary-based approach to improve neuropsychiatric symptom assessment in dementia: A cross-sectional comparison with the neuropsychiatric inventory

    Journal of Alzheimer's Disease
    Abstract

    BackgroundNeuropsychiatric symptoms (NPS) are among the most challenging manifestations of dementia. Currently available assessment tools often fail to fully capture their complexity. Thus, novel...

  • Migeot J, Wen O, Gonzalez-Gomez R, Hernandez H, Aguillon D, Avila-Funes JA, Behrens MI, Bruno MA, Custodio N, Delgado C, Duran-Aniotz C, Duron-Reyes D, García AM, Godoy ME, Hu K, Lawlor B, Li P, Maito MA, Matallana DL, Miller B, de Oliveira MO, Pina-Escudero SD, Possin KL, Resende EPF, Reyes P, Santamaria-Garcia H, Slachevsky A, Takada LT, Vergara P, Yaffe K, Yokoyama JS, Romero-Ortuño R, Ibanez A

    Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America

    Alzheimer's & Dementia
    Abstract

    Introduction: Frailty influences dementia risk and severity. However, its role in differentiating dementia subtypes and associations with brain structural and functional alterations remain...

  • Caro I, Pérez G, Bize JV, Ponferrada J, Ferrante FJ, Welford AS, Gauder L, Olavarría L, Henríquez F, Ramos T, Besnier C, Ferrer L, Gorno-Tempini ML, Slachevsky A, Ibañez A, García AM

    Benchmarking speech biomarkers of Alzheimer's against cognitive and neural measures

    Alzheimer's & Dementia
    Abstract

    Introduction: Digital speech biomarkers (DSBs) support the detection and monitoring of Alzheimer's disease (AD) in Latinos. However, they have not been benchmarked against standard cognitive and...

  • Duran-Aniotz C, Pizarro M, Migeot J, Salazar-Londoño S, Santamaría-García H, O'Bryant SE, Ibanez A

    Contextualizing Blood-Based Biomarkers for Dementia Globally. J Neurochem

    Journal of Neurochemistry
    Abstract

    Blood-based biomarkers (BBMs) are transforming the diagnostic landscape of Alzheimer's disease by enabling scalable, less invasive, and potentially earlier biological characterization. However, most...

  • Tort-Colet N, Stankeviciute L, Fernández-Arcos A, Soldevila-Domenech N, Sánchez-Benavides G, Shekari M, Vállez García D, Altomare D, Barkhof F, Boada M, Buckley C, Collij LE, den Braber A, Farrar G, Ford L, Frisoni GB, Gismondi R, Gispert JD, Grootoonk S, Hanseeuw BJ, Jessen F, Luckett ES, Manber R, Marquié M, Mett A, Quenon L, Ritchie C, Schmidt ME, Schöll M, Stephens AW, Vandenberghe R, Visser PJ, Wolz R, Grau-Rivera O; AMYPAD Consortium

    Self-reported sleep quality and longitudinal amyloid burden in clinically unimpaired adults from the AMYPAD PNHS study

    Alzheimer's Research & Therapy
  • Molina-Berenguer M, Herrero-Martínez D, Vallbona-Garcia A, Vila-Julià F, Cámara Y, Vales Á, González-Aseguinolaza G, Torres-Torronteras J, Martí R

    Systemic delivery of AAV-GFM1 corrects COXPD1 molecular alterations in Gfm1R671C/- mice

    EMBO Molecular Medicine
    Abstract

    Hepatoencephalopathy due to mutations in the nuclear gene GFM1, known as combined oxidative phosphorylation (OXPHOS) deficiency type I (COXPD1), is an autosomal recessive mitochondrial disease caused...

  • Shekari M, Escalante AG, Milà-Alomà M, Falcon C, López-Martos D, Sánchez-Benavides G, Brugulat-Serrat A, Niñerola-Baizán A, Ashton NJ, Karikari TK, Lantero-Rodriguez J, Montoliu-Gaya L, Snellman A, Day TA, Dage JL, Ortiz-Romero P, Tonietto M, Borroni E, Klein G, Kollmorgen G, Carboni M, Quijano-Rubio C, Vanmechelen E, Minguillón C, Fauria K, Perissinotti A, Molinuevo JL, Zetterberg H, Blennow K, Grau-Rivera O, Suárez-Calvet M, Gispert JD; ALFA Study.

    Associations of 18F-RO-948 tau PET with fluid AD biomarkers, Centiloid, and cognition in early AD continuum

    Alzheimer's & Dementia
    Abstract

    Introduction: We examined neurofibrillary tangle (NFT) pathology using 18F-RO-948 tau positron emission tomography (PET) in cognitively unimpaired individuals and its associations with amyloid plaques...

  • Vilor-Tejedor N, van Vorstenbosch R, Evans TE

    Artificial intelligence in dementia care: challenges, controversies, and policy implications

    Frontiers in Dementia
    Abstract

    Artificial intelligence (AI) is rapidly expanding into dementia-related health and social care, with proposed applications ranging from early risk detection and monitoring to care coordination and...

  • Legaz A, Moguilner S, Barttfeld P, Cuadros Castro J, Galván Rial DS, Migeot J, Farina FR, Gonzalez-Gomez R, Salazar-Londoño S, de Souza Azzi T, Alcauter S, Amoruso L, Anghinah R, Bakr M, Behrens MI, Bruno MA, Cardona JF, Chen C, Colliot O, Custodio N, d'Acremont Q, Debette S, Dzianok P, Güntekin B, Huguet J, Jarne C, Joliot M, Karageorgiou E, Khedr EM, Koopowitz SM, Kublik E, Lee J, Aksman L, Lopez S, Margaretic P, Matallana D, Matis S, Miltiadous A, Novotni G, Orio P, Parra MA, Reppermund S, de Paula França Resende E, Salum GA, Slachevsky A, Ortiz ALS, Takada LT, Toh AQ, Tzallas A, Wen W, Whelan R, Yener G, Zegarra Valdivia JA, Alexoudi A, Arshad F, Atta H, Avila-Funes JA, Santos JB, Bruña R, Castelblanco-Toro SM, Chino Vilca BN, Coronel-Oliveros C, Crivello F, Cruzat J, Dellavale D, Dhooge C, Di Caterina G, Escudero J, Esquivias Farias JM, Eze LU, Evans TE, Farombi T, Fernández A, Fittipaldi S, Portillo F, Martinic GF, García AM, Garcia-Cordero I, Gaurav R, Godoy ME, Gonzalez Campo C, González Hernández A, Hanoğlu L, Hazelton JL, Herzog R, Ikiz B, Njamnshi AK, Landin-Romero R, López ME, Maito MA, Medel V, Sepúlveda JPM, Ochoa Gómez JF, Ogbuagu C, de Oliveira MO, Ozansoy M, Palma-Espinosa J, Hilal S, Zhou JH, Escudero SDP, Pitman JK, Prado P, Ramírez González D, Reyes P, Santamaría García H, Schröder J, Sitt JD, Soliman RK, Soto-Añari M, Thanissery N, Ito LT, Tsuchida A, Tzourio C, Yırıkoğulları H, Yokoyama JS, Aguillon D, Miller B, Alladi S, Jiang Y, Navarro A, Babiloni C, Huepe Artigas D, Piguet O, Sosa PAV, Mostert CM, Tahmasian M, Li P, Hu K, Genon S, Stein DJ, Maestú F, Pievani M, Salama M, Brodaty H, Sachdev PS, Lawlor B, Eyre HA, Miranda JJ, Baez S, Tagliazucchi E, Duran-Aniotz C, Hernandez H, Ibanez A.

    The exposome of brain aging across 34 countries

    Nature Medicine
    Abstract

    The physical and social exposome affects human aging, and brain clocks may track its effects. However, most studies neglect multidomain exposures (physical, social and political) across diverse...

  • Rehman D, Chen HY, Lee CC, Vilor-Tejedor N, Upadhyay S, Kuo PC.

    Diffusion-synthesized Chest X-rays improve fairness and diagnostic performance

    PLOS Digital Health
    Abstract

    Deep learning models have been widely applied to chest X-ray (CXR) disease classification and diagnosis; however, challenges such as data scarcity and shortcut learning often lead to biased model...