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publicaciones

Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.

  • Mattsson-Carlgren N, Palmqvist S, Horie K, Barthélemy N, Salvadó G, Binette AP, Tideman P, Morris JC, Benzinger TL, Perrin RJ, Janelidze S, Collij LE, Ossenkoppele R, Schindler SE, Stomrud E, Bateman RJ, Hansson O.

    Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study

    The Lancet Neurology
    Abstract

    Background: Alzheimer's disease pathology can be accurately identified with blood biomarkers (core 1 biomarkers), including plasma p-tau217 tests. Biomarkers that change longitudinally after diagnosis...

  • Hortsch S, Domenico AD, Borlinghaus N, Caley D, Kaminioti-Dumont L, Jeppesen SB, González-Escalante A, Ritchie C, Frederiksen KS, Suárez-Calvet M.

    Performance of a fully automated plasma tau phosphorylated at threonine 217 immunoassay to reflect amyloid-beta burden in an unselected cohort representative of clinical practice

    The journal of prevention of Alzheimer's Disease
    Abstract

    Background: With the emergence of disease-modifying anti-amyloid-beta (Aβ) therapies for Alzheimer's disease (AD), early and accurate quantitative measures of Aβ burden are critical. Blood-based...

  • Salemme S, Mukadam N, Bodryzlova Y, Blossom SCM, Brayne C, Richard E, Seshadri S, Ma'u E, Akinyemi RO, Urso D, Wolters FJ, Grasset L, Dufouil C, Ferri CP, Langa KM, Kalaria R, McKenzie BL, Röhr S, Ibáñez A, Lautenschlage NT, Cullum S, Bobrow K, Anstey KJ, Wallace L, Walsh S; PLADRR Research Group.

    Operationalising dementia prevention as a measurable NCD priority

    The Lancet. Public Health
    Abstract

    Not available

  • Reiman EM, Alexander RC, Langbaum JB, Aisen PS, Ashton N, Atri A, Barbarino P, Byrd GS, Feldman HH, Fowler NR, Ghisays V, Grill JD, Hassenstab J, Heaton GR, Herring WL, Jack CR Jr, Johnson SC, Karlawish J, Keach NL, Kivipelto M, Krumholz HM, Largent EA, MaGee-Rodgers T, McDade E, Mielke MM, Molina-Henry D, Petersen RC, Rabinovici GD, Ritchie C, Schindler SE, Sperling RA, Suárez-Calvet M, Vradenburg G, Weiner MW, Welsh-Bohmer KA, Zetterberg H, Zuendel MT, Mattke S, Cummings JL

    A path to preventing cognitive impairment due to Alzheimer's disease: initiatives beginning in the USA

    The Lancet Neurology
    Abstract

    Antibody therapies can remove amyloid plaques from the brain and slow cognitive decline in people with Alzheimer's disease who are mildly impaired. These drugs are now being evaluated in participants...

  • Suemoto CK, Custodio N, Aguilar D, Avila-Funes JA, Baez S, Bagnati PM, Barnes LL, Brucki SMD, Calandri IL, Caramelli P, Cornejo-Olivas M, Derio CD, Ferreira ST, García AM, Grinberg LT, Ibanez AM, Isasi R, Josephy-Hernández SE, Porras ML, Llibre-Guerra JJ, Llibre-Rodriguez JJ, Lourenco MV, Meza BMM, Migeot J, Miranda JJ, Miranda-Castillo C, Mummery CJ, Parodi JF, Castro NP, Contreras RMS, Santamaría-García H, Slachevsky A, Souza-Talarico JN, Surace EI, Takada LT, Tsoy E, Pilalumbo MU, Zimmer ER, Fontana IC, Mahinrad S, Snyder HM, Carrillo MC.

    The landscape of dementia research, diagnosis, treatment, and care in Latin America

    Alzheimer's & Dementia
    Abstract

    Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed...

  • Daly T, López-Barrenechea I, Vergara P, Arshad F, Paplikar A, Ray Chaudhuri A, Crivelli L, Ibáñez A, Alladi S, Slachevsky A.

    Scientific knowledge about dementia: From the Global South to the world

    Alzheimer's & Dementia
    Abstract

    Most people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines...

  • Timsina J, Jiang C, McCartney DL, Tao F, Dalmasso MC, Najar J, Anastasi F, Ohlei O, Puerta Fuentes R, Yang C, Bradley J, Western D, Ali M, Wang C, Yang C, Wu Y, Liu M, Budde J, Williams J, Mahoney R, Castillo Morales A, Hohman TJ, Dumitrescu L, Wang TC, Tesi N, Kern S, Waern M, Skoog I, van Harten A, Pijnenburg YAL, van der Flier WM, Sánchez-Juan P, Rodriguez-Rodriguez E, Kleineidam L, Peters O, Schneider A, Küçükali F, Bellenguez C, Grenier-Boley B, Heikkinen S, de Rojas I, Rujescu D, Scherbaum N, Hausner L, Düzel E, Grimmer T, Wiltfang J, Vandenberghe R, Engelborghs S, Heilmann-Heimbach S, Schmid M, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Sánchez-Valle R, Álvarez V, García-González P, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Seelaar H, Ramakers I, Papma J, Hulsman M, Laske C, Teipel S, Priller J, Perneczky R, Buerger K, Nöthen MM, Lewczuk P, Kornhuber J, Hampel H, Giegling I, Goldhardt O, Diehl-Schmid J, Andrade V, Heneka MM, Frölich L, Vogelgsang J, Graff C, Thonberg H, Ullgren A, Papenberg G, Deleuze JF, Dufouil C, Wagner M, Jessen F, Holstege H, van Duijn C, Lebouvier T, Hannon O, Leinonen V, Soininen H, Herukka SK, Giedraitis V, Löwenmark M, Kilander L, Genius P, Rodríguez B, Luckett ES, Navarro A, Cano A, Marquié M, Blennow K, Zetterberg H, Lleo A, Boada M, Ruiz A, Lee VM, Van Deerlin VM, Deming Y, Johnson SC, Engelman CD, Pastor P, Alvarez I, Peskind ER, Heslegrave AJ, Saykin AJ, Nho K, Schindler SE, Morris JC, Holtzman DM, McDade E, Renton AE, Goate A, Ibanez L, Riemenschneider M, Albert MS, Laws SM, Porter T, O'Brien EK, Shaw LM, Tijms BM, Ingelsson M, Visser PJ, Hiltunen M, Sleegers K, Ritchie CW, Sims R, Belloy M, Lambert JC, Vilor-Tejedor N, Fernández MV, Li QS, Nagle MW, Marioni RE, Ramirez A, Bertram L, van der Lee SJ, Cruchaga C. 

    GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy

    Nature Communications
    Abstract

    Cerebrospinal fluid amyloid beta 42, total tau, and phosphorylated tau 181 are well accepted markers of Alzheimer's disease. These biomarkers better reflect disease pathogenesis compared to clinical...

  • Ibanez A, Roth N, Colverson A, Bailey C, Miller B, Durón-Reyes DE, Johnson N, Castaner O, Sacco PL, Cotter E, Melloni L.

    Music as a scientific metaphor for mind and brain

    Neuroscience and behavioural reviews
    Abstract

    Metaphors have long played multiple roles in conceptualizing the mind and brain, guiding the development and refinement of theoretical models and empirical questions. Early analogies (comparing the...

  • Scher, M.S., Eyre, H.A., Adalat, S., Hartikainen, K., Berk, M., Ibanez, A. & Markvarde, A. 

    Childhood health through matrescence empowers women to sustain life-course brain health

    npj Women's Health
    Abstract

    The spectrum from normal brain functions to neurological and mental health disorders represents the life-course neural exposome. Proactive interventions strengthen rescue and reparative choices...

  • Kassinopoulos M, Montesinos P, Falcon C, Huguet J, Minguillon C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Zetterberg H, Blennow K, Suárez-Calvet M, Sanchez-Gonzalez J, Gispert JD; ALFA study

    Intracellular fluid accumulation underlies brain volume increases in early Alzheimer's disease

    Brain Communications
    Abstract

    In the preclinical stages of Alzheimer's disease, increased brain volume has been associated with amyloid-beta pathology, particularly in regions that undergo volume reductions as the disease...