Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
Heo G, Xu Y, Wang E, Ali M, Oh HS, Moran-Losada P, Anastasi F, González Escalante A, Puerta R, Song S, Timsina J, Liu M, Western D, Gong K, Chen Y, Kohlfeld P, Flynn A, Thomas AG, Lowery J, Morris JC, Holtzman DM, Perlmutter JS, Schindler SE, Vilor-Tejedor N, Suárez-Calvet M, García-González P, Marquié M, Fernández MV, Boada M, Cano A, Ruiz A, Zhang B, Bennett DA, Benzinger T, Wyss-Coray T, Ibanez L, Sung YJ, Cruchaga C.
Proteomic studies have been instrumental in identifying brain, cerebrospinal fluid and plasma proteins associated with Alzheimer's disease (AD). Here, we comprehensively examined 6,905 aptamers...
Sclafani A, Migueles JH, Olvera-Rojas M, Solis-Urra P, Fernandez-Gamez B, Coca-Pulido A, Bellón D, Fernández-Ortega J, Sanchez-Martinez J, Sánchez-Aranda L, Toval Á, Martín-Fuentes I, Bakker EA, Gispert JD, Triviño-Ibañez EM, Liu-Ambrose T, Erickson KI, Gomez-Rio M, Ortega FB, Esteban-Cornejo I.
Objectives: This study investigated the associations between movement behaviors (physical activity, sedentary behavior, and sleep duration), global and hippocampal amyloid beta levels, and executive...
Carmona R, Roldán G, Fernández-Rueda JL, Navarro A, Peña-Chilet M; CSVS Crowdsourcing Group; Dopazo J, López-López D.
Here we present the Polygenic Score (PGS) distributions for 3124 common diseases and quantitative traits observed in the Spanish population. To achieve so, the genomes and exomes of 2190 unrelated...
Alessiani M, Bonura A, Iaccarino G, Rossi SS, Mangiardi M, Bravi MC, Pezzella FR, de Rubeis G, Pampana E, Anticoli S.
Background and purpose: Distal-medium vessel occlusions (DMVOs) contribute to approximately 25-40 % of cases of ischemic stroke. Intravenous thrombolysis (IVT) achieved a complete recanalization in...
Cumplido-Mayoral I, Sánchez-Benavides G, Vilor-Tejedor N, López-Martos D, Brugulat-Serrat A, Milà-Alomà M, Falcon C, Cacciaglia R, Minguillón C, Fauria K, Kollmorgen G, Quijano-Rubio C, Molinuevo JL, Grau-Rivera O, Suárez-Calvet M, Vilaplana V, Gispert JD
Magnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other...
Palmqvist S, Warmenhoven N, Anastasi F, Pilotto A, Janelidze S, Tideman P, Stomrud E, Mattsson-Carlgren N, Smith R, Ossenkoppele R, Tan K, Dittrich A, Skoog I, Zetterberg H, Quaresima V, Tolassi C, Höglund K, Brugnoni D, Puig-Pijoan A, Fernández-Lebrero A, Contador J, Padovani A, Monane M, Verghese PB, Braunstein JB, Kern S, Blennow K, Ashton NJ, Suárez-Calvet M, Hansson O.
Global implementation of blood tests for Alzheimer's disease (AD) would be facilitated by easily scalable, cost-effective and accurate tests. In the present study, we evaluated plasma phospho-tau217...
Toccaceli Blasi M, Raffaele F, Belvisi D, Buscarnera S, Bruno G, Fabbrini G, Canevelli M.
Introduction: Patients with neurological disorders, particularly those who are chronologically and biologically older, may display highly varied clinical courses and trajectories. The present study...
Palpatzis E, Akinci M, Garcia-Prat M, Blennow K, Zetterberg H, Quijano-Rubio C, Kollmorgen G, Wild N, Gispert JD, Suárez-Calvet M, Grau-Rivera O, Fauria K, Brugulat-Serrat A, Sanchez-Benavides G, Arenaza-Urquijo EM; ALFA stydy
Background and objectives: The prevalence and impact of stressful life events (SLEs) on age-related and Alzheimer disease (AD)-related pathways may depend on social determinants including gender and...
Frisoni GB, Ribaldi F, Allali G, Bieth T, Brioschi Guevara A, Cappa S, Cipolotti L, Frederiksen KS, Georges J, Jessen F, Koch G, Masters H, Mendes AJ, Frölich L, Garibotto V, Grau-Rivera O, Pozzi FE, Religa D, Rostamzadeh A, Shallcross L, Shenkin SD, van der Flier WM, Vernooij MW, Visser LNC, Cummings JL, Scheltens P, Dubois B, Moro E, Bassetti CLA, Kivipelto M.
A European Task Force has recently developed and published the concept and protocols for the setup of the innovative health offer of Brain Health Services for the secondary prevention of dementia and...
Soldevila-Domenech N, Ayala-Garcia A, Barbera M, Lehtisalo J, Forcano L, Diaz-Ponce A, Zwan M, van der Flier WM, Ngandu T, Kivipelto M, Solomon A, de la Torre R.
Preventing dementia and Alzheimer's disease (AD) is a global priority. Multimodal interventions targeting several risk factors and disease mechanisms simultaneously are currently being tested...