Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Martínez-Flores R, Martín-Sobrino I, Falgàs N, Grau-Rivera O, Suárez-Calvet M, Cristi-Montero C, Ibañez A, Fernández-Lebrero A, Contador J, Navalpotro-Gómez I, Puig-Pijoan A, Supèr H.
Cognitive vergence and pupillary responses as functional oculomotor signatures to differentiate AT(N) biological profiles in older adults with mild cognitive impairment
GeroscienceAbstractThe locus coeruleus (LC), the earliest site of tau accumulation in Alzheimer's disease, directly influences pupillary and vergence oculomotor systems. Whether task-evoked oculomotor dynamics can non...
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Fernández-Lebrero A, Jiménez-Balado J, García-Escobar G, Contador J, Estraguès-Gázquez I, Peraferrer-Montesinos L, Manero-Borràs RM, Gramegna LL, Viles M, Campello AR, Ortiz-Romero P, de Diego M, Del Campo M, Torres-Torronteras J, Jiménez-Moyano E, Blasco-Forniés H, Suárez-Calvet M, Ois A, Puig-Pijoan A, Navalpotro-Gómez I.
Plasma p-tau217 detects Alzheimer's disease co-pathology in cerebral amyloid angiopathy: Comparison to CSF biomarkers in the ANGMAR cohort
Alzheimer's & DementiaAbstractIntroduction: Cerebral amyloid angiopathy (CAA) frequently co-occurs with Alzheimer's disease (AD), generating mixed vascular-neurodegenerative phenotypes. Plasma phosphorylated tau (p-tau)217 is a...
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Palpatzis E, Colceriu CM, Shekari M, Akinci M, Suárez-Calvet M, Grau-Rivera O, Sánchez-Benavides G, Gispert JD, Arenaza-Urquijo EM; ALFA study.
Regional amyloid accumulation, post-traumatic distress, and intrusive symptoms in cognitively unimpaired older adults at risk for Alzheimer's
Alzheimer's & DementiaAbstractIntroduction: In preclinical Alzheimer's disease (AD), early pathology may heighten vulnerability to psychiatric symptoms. We examined whether Aβ accumulation in cognitive-emotional regions was...
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Martínez-Flores R, Zapata LP, Del Campo Milan M, Blasco-Forniés H, Jiménez-Moyano E, Torres-Torronteras J, Suárez-Calvet M, Ibáñez A, Martín-Sobrino I, Falgàs N, Grau-Rivera O, Cristi-Montero C, Perone C, Supèr H.
Attentionally directed oculomotor training produces disease-stage-dependent effects on plasma tau, cognition, and oculomotor signatures in patients with mild cognitive impairment
GeroscienceAbstractAttentionally directed oculomotor training may engage circuits implicated in gamma-band modulation and early Alzheimer's disease (AD) pathophysiology, yet its effects across mild cognitive impairment...
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Gallay C, Soldevila-Domenech N, López-Martos D, Sanchez-Benávides G, Huguet J, Suárez-Calvet M, Gispert JD, Salvadó G, Sundermann EE, Grau-Rivera O, Brugulat-Serrat A; for ALFA study.
Effect of Parity and β-Amyloid on Cognition and Hippocampal Volume in Postmenopausal Women
NeurologyAbstractBackground and objectives: Epidemiologic studies exploring the effect of parity on Alzheimer disease (AD) yield mixed results, and little is known about how parity may modify the impact of AD...
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López-Martos D, Suárez-Calvet M, Salvadó G, Cacciaglia R, Shekari M, González-Escalante A, Horta-Barba A, Palma-Gudiel H, Milà-Alomà M, Brugulat-Serrat A, Minguillon C, Tonietto M, Borroni E, Klein G, Quijano-Rubio C, Kollmorgen G, Zetterberg H, Blennow K, Gispert JD, Sánchez-Benavides G, Grau-Rivera O; ALFA study.
Decreased awareness of cognitive decline is associated with multimodal Alzheimer's disease biomarkers in cognitively unimpaired individuals
Neurobiology of AgingAbstractAlzheimer's disease (AD) diagnostic guidelines emphasize subjective cognitive decline (SCD) preceding mild cognitive impairment (MCI), implicitly assuming awareness of cognitive decline (ACD) is...
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Contador J, Pozzi FE, Sánchez-Benavides G, Fernández-Arcos A, Lantero-Rodríguez J, Montoliu-Gaya L, Minguillon C, Fauria K, González-Escalante A, Ortiz-Romero P, Blasco-Forniés H, de Diego-Osaba M, Jiménez Moyano E, Quijano-Rubio C, Kollmorgen G, Le Bastard N, Nadal A, Vanmechelen E, Jeromin A, Torres-Torronteras J, Ashton NJ, Zetterberg H, Blennow K, Gispert JD, Molinuevo JL, Del Campo M, Grau-Rivera O, Suárez-Calvet M; β-AARC Study collaborators.
Detecting amyloid-β pathology in subjective cognitive decline using plasma and CSF biomarkers
EBioMedicineAbstractBackground: Subjective cognitive decline (SCD) may represent an early stage of Alzheimer's disease (AD), but biomarker studies in this population are limited. Therefore, we compared the performance of...
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Serrano-Pozo A, Escott-Price V, Grinberg LT, Pascoal T, Suárez-Calvet M, Dubois B, Sperling RA.
Alzheimer's disease
LancetAbstractAlzheimer's disease is the leading cause of dementia and among the top ten leading causes of death in high-income countries. Exponential advances in epidemiology, genetics, diagnostic imaging and...
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Suárez-Calvet M, Salvadó G, de Fortuny BB, Del Campo M.
Blood biomarkers for Alzheimer's disease: from detection to decisions
Lancet -
Fernández-Lebrero A, Jiménez-Balado J, García-Escobar G, Contador J, Estraguès-Gázquez I, Peraferrer-Montesinos L, Suárez-Pérez A, Manero-Borràs RM, Beltrán B, Gramegna L, Campello AR, Palacio-Gili A, Grau O, Suárez-Calvet M, Ois A, Puig-Pijoan A, Navalpotro-Gómez I.
CSF Biomarker Profile of Cerebral Amyloid Angiopathy: Diagnostic Performance and Imaging Correlates in a Hospital-Based Neurology Cohort
European Journal of NeurologyAbstractBackground: Cerebral amyloid angiopathy (CAA) frequently co-occurs with Alzheimer's disease (AD), complicating diagnosis in patients with cognitive impairment. The CSF biomarker profile of CAA remains...
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