publicaciones

Alzheimer's articles

Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.

  • Serrano-Pozo A, Escott-Price V, Grinberg LT, Pascoal T, Suárez-Calvet M, Dubois B, Sperling RA.

    Alzheimer's disease

    Lancet
    Abstract

    Alzheimer's disease is the leading cause of dementia and among the top ten leading causes of death in high-income countries. Exponential advances in epidemiology, genetics, diagnostic imaging and...

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  • Suárez-Calvet M, Salvadó G, de Fortuny BB, Del Campo M. 

    Blood biomarkers for Alzheimer's disease: from detection to decisions

    Lancet

  • Ibáñez A, Yokoyama JS, Duran-Aniotz C, Miller BL; Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat).

    Genetic-exposome interactions and aging clocks in dementia: the ReDLat2 initiative

    Nature Medicine

  • Manzano Palomo MS, Terrón Cuadrado C, Gil Moreno MJ, Fernández García C, Alonso Bouzón C, Besga Basterra A, Brugulat-Serrat A, Teresa Carreras M, Castellanos Rodrigo M, Delgado Parada E, García Ribas G, Gramunt Fombuena N, Millán Pacheco A, Pagonabarraga Mora J, Porta Etessam J, Ramírez Díaz SP, Isabel Ramos García M, Rodríguez-Sánchez I, Salas Carrillo M, Sánchez-Benavides G, Simal Hernández P, Vieira Campos A.

    Mild functional impairment: Definition and diagnostic criteria

    Neurologia Engl Ed
    Abstract

    Introduction: The onset of mild functional impairment (MFI) is associated with greater progression to cognitive decline, in addition to influencing the course of other neurological, psychiatric, and...

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  • Salvadó G, Horie K, Barthélemy NR, Schindler SE, Janelidze S, Orduña Dolado A, Bali D, Perrin RJ, Morris JC, Benzinger TLS, Gordon BA, Stomrud E, Mattsson-Carlgren N, Palmqvist S, Vogel JW, Bateman RJ, Ossenkoppele R, Hansson O

    Plasma eMTBR-tau243 and %p-tau217 for Biological Staging of Alzheimer Disease

    JAMA Neurology
    Abstract

    Importance: Biological staging of Alzheimer disease (AD) can improve diagnostic accuracy and prognostic assessment. However, existing approaches often require invasive procedures and specialized...

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  • Altschuler F, Castro-Laguardia AM, Canziani V, O'Byrne DF, Hazelton J, Migeot J, Maito M, García AM, Bruno MA, Magrath N, Slachevsky A, Behrens MI, Custodio N, Ávila-Funes JA, Matallana D, Aguillón D, Santamaria-García H, Resende E, Takada L, Brusco LI, Yokoyama JS, Miller B, Ibáñez A, Medel V, Campo CG.

    Mapping the neurovascular landscape in aging and dementia: cerebral small vessel disease markers in a multicenter Latin American cohort

    Alzheimer's & Dementia
    Abstract

    Introduction: Cerebral small vessel disease (CSVD) is a key contributor to cognitive impairment and dementia, yet few studies have compared CSVD across dementia variants, particularly in...

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  • Tahmasian M, Küppers V, Genon S, Eickhoff SB, Golombek DA, Ibanez A. 

    Elevating sleep to a global health priority: The One Sleep Health framework

    Cell Reports Medicine
    Abstract

    Sleep is a non-negotiable necessity for humans and animals and a cornerstone of health. Research is recently undergoing a paradigm shift, moving from a focus on individual factors to macro-level...

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  • König A, Tröger J, Mallick E, Linz N, Ritchie C, Gregory S, Hunter M, Johnson K, Benavides GS, Grau-Rivera O, Radoi A, Porta-Mas C, Köhler S, Teipel S, Hansson O, Tideman P, Wuestefeld A, Palmqvist S.

    Speech-based digital cognitive assessment for clinical trials: Detecting cognitive impairment stages and AD biomarker relations across European cohorts

    Alzheimer's & Dementia
    Abstract

    Introduction: Early detection of Alzheimer's disease (AD) is critical for timely intervention as disease-modifying treatments emerge. Speech-based digital biomarkers offer scalable options for...

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  • Otero M, Carriel-Rubilar FI, Hernandez H, Cuadros J, Condado JG, Sainz-Ballesteros A, Santamaria-Garcia H, Legaz A, Birba A, Fittipaldi S, Lopera F, Ochoa-Gómez J, Aguillon D, González-Hernández A, Bonilla-Santos J, Gonzalez-Montealegre RA, Yener GG, Güntekin B, Kıyı İ, Aktürk T, Yıldırım E, Hanoğlu L, Anghinah R, Valdes-Sosa PA, Garcia-Reyes R, Escudero J, Lopez S, Whelan R, Fernández A, García AM, Huepe D, Soto-Añari M, Herrera E, Abasolo D, Rubido N, Clark RA, El-Deredy W, Cortes JM, Parra MA, Babiloni C, Ibanez A, Prado P.

    Source-space EEG alpha activity reveals brain age gaps due to neurodegeneration and disparity

    Communications Biology
    Abstract

    Brain clocks are promising tools for evaluating brain health. However, most current methods rely on structural neuroimaging. Functionally based approaches remain scarce, especially for assessing age...

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  • Fernández-Lebrero A, Jiménez-Balado J, García-Escobar G, Contador J, Estraguès-Gázquez I, Peraferrer-Montesinos L, Suárez-Pérez A, Manero-Borràs RM, Beltrán B, Gramegna L, Campello AR, Palacio-Gili A, Grau O, Suárez-Calvet M, Ois A, Puig-Pijoan A, Navalpotro-Gómez I.

    CSF Biomarker Profile of Cerebral Amyloid Angiopathy: Diagnostic Performance and Imaging Correlates in a Hospital-Based Neurology Cohort

    European Journal of Neurology
    Abstract

    Background: Cerebral amyloid angiopathy (CAA) frequently co-occurs with Alzheimer's disease (AD), complicating diagnosis in patients with cognitive impairment. The CSF biomarker profile of CAA remains...

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