Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Juantorena GE, Capelo G, Leon Vallejos BD, Ibáñez A, Petroni A, Berrios W, Fernández MC, Kamienkowski JE
Machine learning based digital assessment of mild cognitive impairment using mouse trajectories during the trail making test
Scientific ReportsAbstractOne of the objectives of digital neuropsychology is to apply computational methods to improve the accuracy of traditional assessments. The Trail Making Test (TMT) is one of the most popular...
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Bellomo G, Vermunt L, In 't Veld S, Doecke JD, Hok-A-Hin YS, Veverová K, Houtkamp IM, Alcolea D, Halbgebauer S, Quesada C, Mattsson N, Martinez-Castillo M, López-Martínez MJ, Rábano A, Boonkamp L, Fowler C, Fortea J, Gaetani L, Toja A, Pijnenburg Y, Lemstra A, van der Flier WM, Sánchez-Juan P, Hort J, Otto M, Anderl-Staub S, Sieben A, de Viel B, Engelborghs S, Hansson O, Masters C, Lleó A, Parnetti L, Teunissen CE, Del Campo M.
Plasma proteome profiling identified biomarkers for the differential diagnosis and molecular staging of neurodegenerative dementias
Nature AgingAbstractBlood-based biomarkers are emerging as scalable tools for the diagnosis and monitoring of neurodegenerative diseases, but markers enabling differential diagnosis across major dementias remain limited...
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Grueso S, Sánchez-Benavides G, Santos-Santos M, Subirats L, Prados F, Grau-Rivera O, Calabria M.
Bilingualism and cognition: The impact of age of acquisition, language use, and proficiency in cognitively unimpaired older adults
Journal of Alzheimer's DiseaseAbstractBackground: The positive effect of bilingualism as a cognitive reserve factor in aging remains inconclusive, with inconsistencies often stemming from treating bilingualism as a dichotomous variable...
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Migeot J, Wen O, Olivares D, Morales JP, Franco-O'Byrne D, Rodriguez-Villagra OA, Ibañez A, Huepe D.
Socioeconomic status impacts metacognition of working memory and emotion recognition
NeuroscienceAbstractSocioeconomic status (SES) affects a wide range of cognitive functions. Still, its influence on metacognition, a second-order, integrative, and regulatory cognitive process, remains unknown. We...
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Bassetti CLA, Chen C, Lewis SL, Bègue I, Adorjan K, Aguilar D, Alladi S, Bhidayasiri R, Bhatia KP, Boon P, Bustín J, Cetkovich M, Couto B, Custodio N, Datta AN, Debette S, Dhamija RK, Dorman G, Du Plessis S, Elkind MSV, Fiorillo A, Gershanik O, Golombek DA, Toledo MEG, Ibáñez A, Irarrázaval M, Leonardi M, Lustenberger C, Mintzer J, Murthy P, Njamnshi AK, O'Neill S, Padovani A, Pike J, Piguet O, Piovesana E, Rejdak K, Roca M, Rodríguez J, Rost NS, Santamaria-Garcia H, Shallcross L, Slachevsky A, Torralva T, Valcour V, Wang Y, Winkler AS, Wasserman D, Manes F
The International Alliance on Brain Health (IABH): Bridging global efforts toward integrated brain and mental health plans and the promotion of local implementations
Journal of the neurological sciencesAbstractThe convergence of neurological, psychiatric, neurodevelopmental, and public health approaches to brain health is reshaping global strategies for prevention, care, and policy. However, major gaps...
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Soldevila-Domenech N, Ayala-Garcia A, Zhou X, Yi SY, Ros E, Sala-Vila A, Lehtisalo J, Steffen LM, de la Torre R; IAFNS Retrospective Harmonization Expert Working Group; Blackwell CK, Khoo C, Mansolf MA, Ros E, Snetselaar L, Wey T.
Diet and Cognitive Function in Aging: An Individual Participant Data Meta-Analysis from Eight Cohorts in Europe and the United States
The Journal of NutritionAbstractBackground: Cognitive decline is a major public health concern as populations age. Diet is a modifiable contributor to cognitive health, yet observational findings remain inconsistent, partly due to...
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Pieperhoff L, Lorenzini L, Almeida F, Tranfa M, Bollack A, Arunachalam P, Masserini F, Wolz R, Grootoonk S, Ritchie C, Boada M, Marquié M, Vijverberg J, Vandenberghe R, Hanseeuw BJ, Martinez-Lage P, Payoux P, Visser PJ, Schöll M, Frisoni GB, Pardini M, Roccataglia L, Stephens AW, Buckley C, Farrar G, Jessen F, Gispert JD, Salvadó G, Luckett ES, Mutsaerts HM, Wink AM, Collij LE, Barkhof F, Oliveira TG; AMYPAD consortium.
Cortical gray-white matter contrast alterations precede amyloid-β positivity and macrostructural changes in older adults without dementia
Alzheimer's & DementiaAbstractIntroduction: Early Alzheimer's disease (AD) involves subtle cortical changes that may precede atrophy. Magnetic resonance imaging (MRI) microstructural markers may detect earlier pathology than...
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Gallay C, Soldevila-Domenech N, López-Martos D, Sanchez-Benávides G, Huguet J, Suárez-Calvet M, Gispert JD, Salvadó G, Sundermann EE, Grau-Rivera O, Brugulat-Serrat A; for ALFA study.
Effect of Parity and β-Amyloid on Cognition and Hippocampal Volume in Postmenopausal Women
NeurologyAbstractBackground and objectives: Epidemiologic studies exploring the effect of parity on Alzheimer disease (AD) yield mixed results, and little is known about how parity may modify the impact of AD...
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Vidal V, Farías G, Delgado C, Delano PH, Vergara RC, Orellana P, Ossandón T, Crossley NA, Gonzalez-Campo C, Naismith SL, Gonzalez-Gomez R, Coronel-Oliveros C, Ibáñez A, Wainstein G, Sanders RD, Shine JM, Medel V.
White matter hyperintensities are associated with locus coeruleus atrophy and astrocytic β2-adrenergic receptor expression.
Alzheimer's & DementiaAbstractIntroduction: White matter hyperintensities (WMHs) are a robust marker of brain aging and dementia risk, typically attributed to vascular pathology. However, impaired astrocytic support may also...
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