Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Torrealba E, Garcia-Morales P, Cejudo JC, Diaz M, Rodriguez-Esparragon F, Fabre O, Mesa-Herrera F, Marin R, Sanchez-Garcia F, Rodriguez-Perez A, Gramunt N.
In-Out-Test: A New Paradigm for Sorting the Wheat from the Chaff in Prodromal Alzheimer's Disease
Journal of Alzheimer's DiseaseAbstractBackground: Assessment of hippocampal amnesia is helpful to distinguish between normal cognition and mild cognitive impairment (MCI), but not for identifying converters to dementia. Here biomarkers...
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Marchant NL, Barnhofer T, Klimecki OM, Poisnel G, Lutz A, Arenaza-Urquijo E, Collette F, Wirth M, Schild AK, Coll-Padrós N, Reyrolle L, Horney D, Krolak-Salmon P, Molinuevo JL, Walker Z, Maillard A, Frison E, Jessen F, Chételat G, SCD-WELL Medit-Ageing Research Group
The SCD-Well randomized controlled trial: Effects of a mindfulness-based intervention versus health education on mental health in patients with subjective cognitive decline (SCD)
Alzheimer's & Dementia: Translational Research & Clinical InterventionsAbstractIntroduction: Subjectively experienced cognitive decline in older adults is an indicator of increased risk for dementia and is also associated with increased levels of anxiety symptoms. As anxiety is...
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Cummings JL, Atri A, Ballard C, Boneva N, Frölich L, Molinuevo JL, Raket LL, Tariot PN.
Insights into globalization: comparison of patient characteristics and disease progression among geographic regions in a multinational Alzheimer's disease clinical program
Alzheimer's Research & TherapyAbstractBackground: Globalization of clinical trials has important consequences for trial planning and interpretation. This study investigated heterogeneity in patient characteristics and outcomes among world...
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Vilor-Tejedor N , Alemany S, Cáceres A, Bustamante M, Pujol J, Sunyer J, González JRStrategies for integrated analysis in imaging genetics studies
Neuroscience & Biobehavioral ReviewsAbstractImaging Genetics (IG) integrates neuroimaging and genomic data from the same individual, deepening our knowledge of the biological mechanisms behind neurodevelopmental domains and neurological... -
Shaw LM, Arias J, Blennow K, Galasko D, Molinuevo JL, Salloway S, Schindler S, Carrillo MC, Hendrix JA, Ross A, Illes J, Ramus C, Fifer S
Appropriate use criteria for lumbar puncture and cerebrospinal fluid testing in the diagnosis of Alzheimer's disease
Alzheimer's & DementiaAbstractIntroduction: The Alzheimer's Association convened a multidisciplinary workgroup to develop appropriate use criteria to guide the safe and optimal use of the lumbar puncture procedure and... -
Hampel H, O'Bryant SE, Molinuevo JL, Zetterberg H, Masters CL, Lista S, Kiddle SJ, Batrla R, Blennow K
Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic
Nature Reviews NeurologyAbstractBiomarker discovery and development for clinical research, diagnostics and therapy monitoring in clinical trials have advanced rapidly in key areas of medicine - most notably, oncology and... -
Rhodius-Meester HFM, Liedes H, Koikkalainen J, Wolfsgruber S, Coll-Padros N, Kornhuber J, Peters O, Jessen F, Kleinidam L, Molinuevo JL, Rami L, Teunissen CE, Barkhof F, Sikkes SAM, Wesselman LMP, Slot RER, Verfaillie SCJ, Scheltens P, van der Flier WM
Computer-assisted prediction of clinical progression in the earliest stages of AD
Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringAbstractIntroduction: Individuals with subjective cognitive decline (SCD) are at increased risk for clinical progression. We studied how combining different diagnostic tests can help to identify individuals... -
Hu X, Teunissen C, Spottke A, Heneka MT, Düzel E, Peters O, Li S, Priller J, Bürger K, Teipel S, Laske C, Verfaillie S, Barkhof F, Coll-Padrós N, Rami L, Molinuevo JL, van der Flier W, Jessen F
Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies
Alzheimer's DementiaAbstractIntroduction: Previous studies showed associations of brain volume differences and biomarker evidence for Alzheimer's disease (AD) in subjective cognitive decline (SCD). The consistency of this... -
Monté-Rubio GC, Falcón C, Pomarol-Clotet E, Ashburner J
A comparison of various MRI feature types for characterizing whole brain anatomical differences using linear pattern recognition methods
NeuroImageAbstractThere is a widespread interest in applying pattern recognition methods to anatomical neuroimaging data, but so far, there has been relatively little investigation into how best to derive image... -
Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R, Gabel S, Schaeverbeke J, Scheltens P, Blin O, Richardson JC, Bordet R, Wallin A, Eckerstrom C, Molinuevo JL, Engelborghs S, Van Broeckhoven C, Martinez-Lage P, Popp J, Tsolaki M, Verhey FRJ, Baird AL, Legido-Quigley C, Bertram L, Dobricic V, Zetterberg H, Lovestone S, Streffer J, Bianchetti S, Novak GP, Revillard J, Gordon MF, Xie Z, Wottschel V, Frisoni G, Visser PJ, Barkhof F
MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study
Alzheimer's Research & TherapyAbstractBackground: With the shift of research focus towards the pre-dementia stage of Alzheimer's disease (AD), there is an urgent need for reliable, non-invasive biomarkers to predict amyloid pathology. The...
