Alzheimer's articles
Scientific articles published by the researchers of Barcelonaβeta Brain Research Center (BBRC), related to Alzheimer's disease, neuroimaging, memory and neurodegenerative diseases, among other fields.
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Gispert JD, Monté GC, Suárez-Calvet M, Falcon C, Tucholka A, Rojas S, Rami L, Sánchez-Valle R, Lladó A, Kleinberger G, Haass C, Molinuevo JL
The APOE ε4 genotype modulates CSF YKL-40 levels and their structural brain correlates in the continuum of Alzheimer's disease but not those of sTREM2
Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringAbstractIntroduction: Among other metabolic functions, the apolipoprotein E (APOE) plays a crucial role in neuroinflammation. We aimed at assessing whether APOE ε4 modulates levels of glial cerebrospinal...
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Lewczuk P, Matzen A, Blennow K, Parnetti L, Molinuevo JL, Eusebi P, Kornhuber J, Morris JC, Fagan AM.
Cerebrospinal Fluid A beta(42/40) Corresponds Better than A beta(42) to Amyloid PET in Alzheimer's Disease
Journal of Alzheimer's DiseaseAbstractBackground: Decreased concentrations of amyloid-β 1-42 (Aβ42) in cerebrospinal fluid (CSF) and increased retention of Aβ tracers in the brain on positron emission tomography (PET) are considered the...
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Padayachee ER, Zetterberg H, Portelius E, Borén J, Molinuevo JL, Andreasen N, Cukalevski R, Linse S, Blennow K, Andreasson U.
Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele
Brain ResearchAbstractMisfolding and aggregation of amyloid β (Aβ) are key features of Alzheimer's disease (AD) pathogenesis, but the molecular events controlling this process are not known in detail. In vivo, Aβ...
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Shakeri M, Lombaert H, Datta AN, Oser N, Létourneau-Guillon L, Lapointe LV, Martin F, Malfait D, Tucholka A, Lippé S, Kadoury S, Alzheimer's Disease Neuroimaging Initiative.
Statistical shape analysis of subcortical structures using spectral matching
Computerized Medical Imaging and GraphicsAbstractStudying morphological changes of subcortical structures often predicate neurodevelopmental and neurodegenerative diseases, such as Alzheimer's disease and schizophrenia. Hence, methods for...
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Berthier ML, Roé-Vellvé N, Moreno-Torres I, Falcon C, Thurnhofer-Hemsi K, Paredes-Pacheco J, Torres-Prioris MJ, De-Torres I, Alfaro F, Gutiérrez-Cardo AL, Baquero M, Ruiz-Cruces R, Dávila G.
Mild Developmental Foreign Accent Syndrome and Psychiatric Comorbidity: Altered White Matter Integrity in Speech and Emotion Regulation Networks
Frontiers in Human NeuroscienceAbstractForeign accent syndrome (FAS) is a speech disorder that is defined by the emergence of a peculiar manner of articulation and intonation which is perceived as foreign. In most cases of acquired FAS...
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Modeling practice effects in healthy middle-aged participants of the Alzheimer and Families parent cohort
Alzheimer's & Dementia: Diagnosis, Assessment & Disease MonitoringAbstractIntroduction: Repetitive administration of neuropsychological tests can lead to performance improvement merely due to previous exposure. The magnitude of such practice effects (PEs) may be used as a...
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Demirtaş M, Tornador C, Falcón C, López-Solà M, Hernández-Ribas R, Pujol J, Menchón JM, Ritter P, Cardoner N, Soriano-Mas C, Deco G.
Dynamic functional connectivity reveals altered variability in functional connectivity among patients with major depressive disorder
Human Brain MappingAbstractResting-state fMRI (RS-fMRI) has become a useful tool to investigate the connectivity structure of mental health disorders. In the case of major depressive disorder (MDD), recent studies regarding the...
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Sánchez-Benavides G, Peña-Casanova J, Casals-Coll M, Gramunt N, Manero RM, Puig-Pijoan A, Aguilar M, Robles A, Antúnez C, Frank-García A, Fernández-Martínez M, Blesa R, NEURONORMA Study Team
One-Year Reference Norms of Cognitive Change in Spanish Old Adults: Data from the NEURONORMA Sample.
Archives of Clinical NeuropsychologyAbstractObjective: Serial cognitive assessments are useful for many purposes, such as monitoring cognitive decline or evaluating the result of an intervention. In order to determine if an observed change is...
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Molinuevo JL, Gramunt N, Gispert JD, Fauria K, Esteller M, Minguillon C, Sánchez-Benavides G, Huesa G, Morán S, Camí J.
The ALFA project: a research platform to identify early pathophysiological features of Alzheimer’s disease
Alzheimer's & Dementia: Translational Research & Clinical InterventionsAbstractIntroduction: The preclinical phase of Alzheimer's disease (AD) is optimal for identifying early pathophysiological events and developing prevention programs, which are shared aims of the ALFA project...
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Aparicio J, Carreño M, Bargalló N, Setoain X, Rubí S, Rumià J, Falcón C, Calvo A, Martí-Fuster B, Padilla N, Boget T, Pintor L, Donaire A.
Combined 18F-FDG-PET and diffusion tensor imaging in mesial temporal lobe epilepsy with hippocampal sclerosis
Neuroimage: ClinicalAbstractObjectives: Several studies using 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) or diffusion tensor imaging (DTI) have found both temporal and extratemporal abnormalities in...
