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The Barcelonaβeta Dementia Prevention Research Clinic is a pioneering research project that studies the risk, and its biological bases, of developing dementia within 5-years in people with subjective memory complaints. The study was launched in May 2018, lasts 3 years and will incorporate 400 participants between 60 and 80 years old, who are experiencing a decrease in memory or other cognitive abilities, but who have not been diagnosed with Alzheimer's disease or any other form of dementia or disease that could justify it.

The project will offer participants a customized and individualized action plan to reduce their risk. This plan consists of a series of advice aimed at the reduction of modifiable risk factors of the disease, and contemplates the possibility of offering participation in specific studies of detection and prevention of Alzheimer's disease to those people who meet the corresponding criteria.

Participants are visited by a neurologist at the facilities of Barcelonaβeta Brain Research Center, where they are also subjected to cognitive, neuroimaging and genetic tests. Based on the information gathered in these tests, an algorithm is applied that calculates the estimated risk percentage of suffering dementia in the next 5 years.

In addition to investigating if there is a biological basis associated with the calculated risk algorithm, the project also studies the possible emotional impact that the fact of individually revealing this risk percentage may have, as well as the benefits that may be derived from participation in the study. Each participant will have a personalized follow-up that will last a total of 1 year.

Unidad de Investigación Clínica en Prevención de la Demencia
The project estimates the risk of suffering dementia in individuals with subjective cognitive decline